Browse our anti-RIPK1 (RIPK1) Antibodies

Full name:
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 Antibodies (RIPK1)
On are 137 Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Antibodies from 25 different suppliers available. Additionally we are shipping RIPK1 Proteins (29) and RIPK1 Kits (14) and many more products for this protein. A total of 191 RIPK1 products are currently listed.
2400006N03Rik, C9orf12, D330015H01Rik, RGD1311271, Rinp, Rip, Rip1, rIpk1, RP23-83I13.5
list all antibodies Gene Name GeneID UniProt
RIPK1 306808 Q5PXE9
RIPK1 8737 Q13546
RIPK1 19766 Q60855

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anti-Rat (Rattus) RIPK1 Antibodies:

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anti-Mouse (Murine) RIPK1 Antibodies:

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Top referenced anti-RIPK1 Antibodies

  1. Chicken Monoclonal RIPK1 Primary Antibody for IF, IP - ABIN967984 : Takahashi, Tanaka, Brannan, Jenkins, Copeland, Suda, Nagata: Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. in Cell 1994 (PubMed)
    Show all 5 references for 967984

  2. Human Polyclonal RIPK1 Primary Antibody for ELISA, ICC - ABIN4350584 : Nilsson, Loganathan, Sekiguchi, Matsuba, Hui, Tsubuki, Tanaka, Iwata, Saito, Saido: Aβ secretion and plaque formation depend on autophagy. in Cell reports 2013 (PubMed)
    Show all 3 references for 4350584

  3. Human Polyclonal RIPK1 Primary Antibody for IHC (p), WB - ABIN657814 : Kim, Ohoka, Okuhira, Sai, Nishimaki-Mogami, Naito: Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α-induced apoptosis. in Cancer science 2010 (PubMed)
    Show all 2 references for 657814

  4. Human Polyclonal RIPK1 Primary Antibody for IHC (fro), IHC (p) - ABIN127073 : Hsu, Huang, Shu, Baichwal, Goeddel: TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. in Immunity 1996 (PubMed)
    Show all 2 references for 127073

  5. Human Polyclonal RIPK1 Primary Antibody for IF (p), IHC (p) - ABIN715016 : Luo, Roy, Xiao, Sun, Liang, Chen, Fu, Sun, Zhu, Ye, Liu: Lycorine induces programmed necrosis in the multiple myeloma cell line ARH-77. in Tumour biology 2014 (PubMed)
    Show all 2 references for 715016

  6. Human Monoclonal RIPK1 Primary Antibody for IP, WB - ABIN967307 : Stanger, Leder, Lee, Kim, Seed: RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. in Cell 1995 (PubMed)

  7. Cow (Bovine) Polyclonal RIPK1 Primary Antibody for WB - ABIN2792131 : Kurenova, Xu, Yang, Baldwin, Craven, Hanks, Liu, Cance: Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. in Molecular and cellular biology 2004 (PubMed)

More Antibodies against RIPK1 Interaction Partners

Human Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) interaction partners

  1. UL45 promoted the UL48-RIP1 (show UQCRFS1 Antibodies) interaction and re-localization of RIP1 (show UQCRFS1 Antibodies) to the UL48-containing virion assembly complex.

  2. we provide evidence that p62 (show GTF2H1 Antibodies) is implicated in the activation of NF-kappaB (show NFKB1 Antibodies) signaling that is partly dependent on RIP1 (show UQCRFS1 Antibodies)

  3. inactivation of RIP1 (show UQCRFS1 Antibodies)/RIP3 (show RIPK3 Antibodies) resulted in reduction of SOCS1 (show SOCS1 Antibodies) protein levels and partial differentiation of AML (show RUNX1 Antibodies) cells. AML (show RUNX1 Antibodies) cells with inactivated RIP1 (show UQCRFS1 Antibodies)/RIP3 (show RIPK3 Antibodies) signaling show increased sensitivity to IFN-gamma-induced (show SAMHD1 Antibodies) differentiation.

  4. Data show that pan (show SUPT6H Antibodies)-caspase (show CASP3 Antibodies) inhibitors facilitated 5-fluorouracil (5-FU)-induced necroptosis mediated by secretion of tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies)) driven by nuclear factor kappaB (NF-kappaB (show NFKB1 Antibodies)) and required RIP1 (show UQCRFS1 Antibodies) kinase.

  5. RIPK1 kinase activity is a pertinent therapeutic target to protect liver against excessive cell death in liver diseases.

  6. Ripk1 is directly involved in apoptosis/necroptosis. In osteosarcoma cells( OS) , small interfering RNA against Ripk1 prevented cell death induced by the sequestration of miR (show MLXIP Antibodies)-155-5p. Collectively, we show that miR (show MLXIP Antibodies)-148a-3p and miR (show MLXIP Antibodies)-155-5p are species-conserved deregulated miRNA in OS

  7. RIPK1 collaborates with TRAF2 (show TRAF2 Antibodies) to inhibit murine and human hepatocarcinogenesis.

  8. Necroptosis signaling is modulated by the kinase RIPK1 and requires the kinase RIPK3 and the pseudokinase MLKL. (Review)

  9. CYLD (show CYLD Antibodies) Promotes TNF-alpha (show TNF Antibodies)-Induced Cell Necrosis Mediated by RIP-1 (show UQCRFS1 Antibodies) in Human Lung Cancer Cells

  10. TRAIL can enhance RIP1 (show UQCRFS1 Antibodies) and c-FLIPL (show CFLAR Antibodies) expression in HepG2 cells.

Mouse (Murine) Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) interaction partners

  1. MK2 (show KCNA2 Antibodies)-mediated phosphorylation of RIPK1 serves as a checkpoint within the TNF (show TNF Antibodies) signaling pathway that integrates cell survival and cytokine production.

  2. study identifies a novel role for RIPK1 and RIPK3 (show RIPK3 Antibodies), a pair of homologous serine/threonine kinases previously implicated in the regulation of necroptosis and pathologic tissue injury, in directing IFN-beta (show IFNB1 Antibodies) production in macrophagesges.

  3. this study shows that RIPK1 and RIPK3 (show RIPK3 Antibodies) account for acute inflammatory responses induced by lipopolysaccharide in vivo; notably, this regulation does not require exogenous manipulation of caspases

  4. these findings indicate that RIPK1 cooperates with NF-kappaB (show NFKB1 Antibodies) signaling to prevent TNFR1 (show TNFRSF1A Antibodies)-independent hepatocyte apoptosis and the development of chronic liver disease and cancer, but acts downstream of TNFR1 (show TNFRSF1A Antibodies) signaling to promote diethylnitrosamine-induced liver tumorigenesis.

  5. this study reveals a critical kinase-independent platform role for RIPK1 in protecting against TNF (show TNF Antibodies)/caspase (show CASP3 Antibodies)-dependent apoptosis of hepatocytes in immune-mediated liver injury

  6. Results revealed that RIPK1 and PGAM5 (show PGAM5 Antibodies) function independently to exert optimal control of Leishmania replication in the host.

  7. Knocking down receptor-interacting serine/threonine protein kinase 1 (Ripk1) increased both intracellular and extracellular PGRN (show GRN Antibodies) protein levels by increasing the translation rate of PGRN (show GRN Antibodies) without affecting mRNA levels.

  8. The findings reported here indicate that palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation of RAW 264.7 cells in the plasma membrane, which could provide a new mechanism to explain the link between elevated levels of free fatty acids (FFAs), palmitate in particular, and macrophage death.

  9. The results indicate that RIP1 and MLKL contribute to necroptotic cell death after HCoV-OC43 infection to limit viral replication.

  10. this study reveals a unique response of Kupffer cells against liver ischemia reperfusion, that is, RIP1 (show RALBP1 Antibodies)-dependent necrosis, which constitutes a novel mechanism of liver inflammatory immune activation in the pathogenesis of liver ischemia reperfusion injury

RIPK1 Antigen Profile

Antigen Summary

Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.

Alternative names and synonyms associated with RIPK1

  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (LOC100230522) antibody
  • inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Ippk) antibody
  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1) antibody
  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1) antibody
  • RPA interacting protein (Rpain) antibody
  • 2400006N03Rik antibody
  • C9orf12 antibody
  • D330015H01Rik antibody
  • RGD1311271 antibody
  • Rinp antibody
  • Rip antibody
  • Rip1 antibody
  • rIpk1 antibody
  • RP23-83I13.5 antibody

Protein level used designations for RIPK1

receptor (TNFRSF)-interacting serine-threonine kinase 1 , 1,3,4,5,6-pentakisphosphate 2-kinase , inositol polyphosphate kinase 1 , inositol-1,3,4,5,6-pentakisphosphate 2-kinase , inositol-pentakisphosphate 2-kinase , ins(1,3,4,5,6)P5 2-kinase , insP5 2-kinase , RIP-1 , cell death protein RIP , receptor interacting protein , receptor-interacting protein 1 , receptor-interacting serine/threonine-protein kinase 1 , serine/threonine-protein kinase RIP , RPA interacting protein delta 2 , RPA interacting protein epsilon , RPA-interacting protein

100230522 Taeniopygia guttata
306808 Rattus norvegicus
8737 Homo sapiens
504727 Bos taurus
100524751 Sus scrofa
19766 Mus musculus
306886 Rattus norvegicus
69723 Mus musculus
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