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anti-Rat (Rattus) TRADD antibody for Immunofluorescence

Recommended TRADD Antibody (supplied by: Log in to see )

Antigen
TNFRSF1A-Associated Via Death Domain (TRADD) Antibodies
  • 9130005N23Rik
  • AA930854
  • Hs.89862
  • TRADD
  • tradd
  • wu:fc59e02
  • zgc:103556
Epitope
AA 163-312
17
17
16
11
6
5
5
5
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
90
29
19
5
4
3
2
2
2
Host
Mouse
99
8
Clonality
Monoclonal
Conjugate
This TRADD antibody is un-conjugated
5
5
2
2
2
2
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
90
46
45
23
19
17
12
11
4
2
1
1
1
1
Supplier
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Catalog No. ABIN968045
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3161046 ABIN968046 IF IP IHC WB Mouse IgG1 AA 163-312 Log in to see 37-TRADD 5

Top referenced anti-TRADD antibody for Immunofluorescence

Similar anti-TRADD Antibodies

Application / Reactivity Rat (Rattus) Human
ELISA 6 Antibodies 36 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 9 Antibodies
Immunofluorescence (IF) 2 Antibodies 20 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 10 Antibodies 47 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Immunoprecipitation (IP) 4 Antibodies
Western Blotting (WB) 17 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 17 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies

General

Antigen TNFRSF1A-Associated Via Death Domain (TRADD) Antibodies
Epitope AA 163-312
(17), (17), (16), (11), (6), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(90), (29), (19), (5), (4), (3), (2), (2), (2)
Host Mouse
(99), (8)
Clonality (Clone)
Monoclonal   ( )
Conjugate This TRADD antibody is un-conjugated
(5), (5), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(90), (46), (45), (23), (19), (17), (12), (11), (4), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-TRADD Antibody

Target Details TRADD Application Details Handling References for anti-TRADD Antibody (ABIN968045) Images
Cross-Reactivity Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human TRADD aa. 163-312
Clone 37-TRADD
Isotype IgG1

Target Details TRADD

Product Details anti-TRADD Antibody Application Details Handling References for anti-TRADD Antibody (ABIN968045) Images back to top
Antigen
Alternative Name TRADD (TRADD Antibody Abstract)
Background TNFalpha (Tumor Necrosis Factor) stimulates programmed cell death and NF-kappaB activation as a result of its binding to the TNF receptor 1 (TNFR1). Within this receptor, a sequence referred to as the death domain” has been shown to be necessary for both of these functions. Using the yeast two-hybrid system to detect proteins which interact with the receptor through this death domain”, a 34 kDa protein was found and designated TRADD (TNFR1-Associated Death Domain protein). TRADD appears to contain no intrinsic catalytic activity. It also contains a death domain and it has been shown to bind to FADD and RIP. Mutational analysis of TRADD demonstrates that programmed cell death and NF-kappaB activation are distinct and controlled independently.
Synonyms: TNFR1-Associated Death Domain protein
Molecular Weight 34 kDa
Research Area Cardiovascular, Atherosclerosis, Apoptosis/Necrosis
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-TRADD Antibody Target Details TRADD Handling References for anti-TRADD Antibody (ABIN968045) Images back to top
Comment

Related Products: ABIN968537, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-TRADD Antibody Target Details TRADD Application Details References for anti-TRADD Antibody (ABIN968045) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20° C.

References for anti-TRADD Antibody (ABIN968045)

Product Details anti-TRADD Antibody Target Details TRADD Application Details Handling Images back to top
Product cited in:

He, Ting: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, 2002

Morgan, Thorburn, Pandolfi, Thorburn: "Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 975-84, 2002

Yount, Afshar, Ries, Korn, Shalev, Basila, McCormick, Haas-Kogan: "Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells." in: Oncogene, Vol. 20, Issue 22, pp. 2826-35, 2001

Park, Baichwal: "Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD." in: The Journal of biological chemistry, Vol. 271, Issue 16, pp. 9858-62, 1996

Background publications

Hsu, Xiong, Goeddel: "The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation." in: Cell, Vol. 81, Issue 4, pp. 495-504, 1995

Images

Product Details anti-TRADD Antibody Target Details TRADD Application Details Handling References for anti-TRADD Antibody (ABIN968045) back to top
Supplier Images
Western Blotting (WB) image for anti-TRADD antibody (TNFRSF1A-Associated Via Death Domain) (AA 163-312) (ABIN968045) Western blot analysis of TRADD on a Jurkat cell lysate (Human T-cell leukemia, ATCC T...
Immunofluorescence (IF) image for anti-TRADD antibody (TNFRSF1A-Associated Via Death Domain) (AA 163-312) (ABIN968045) Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC ...