Browse our Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) ELISA Kits

On www.antibodies-online.com are 76 Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) ELISA Kits from 11 different suppliers available. Additionally we are shipping Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Antibodies (303) and Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Proteins (17) and many more products for this protein. A total of 404 Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) products are currently listed.
Synonyms:
GCCR, GCL, GCR, gr, GR-A, GRL, Grl-1, Grl1, LOC100302444, NO, nr3c1, xGR, zgc:113038
list all ELISA KIts Gene Name GeneID UniProt
NR3C1 24413 P06536
NR3C1 14815  
NR3C1 2908 P04150

Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) ELISA Kits by Reactivity

More ELISA Kits for Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) Interaction Partners

Zebrafish Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

Mouse (Murine) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. Skin differentiation is impaired, and both apoptosis and cell proliferation are augmented in the absence of p23 (show CDK5R1 ELISA Kits); the consequences are a severe thinning of the stratum corneum and reduced numbers of hair follicles. Since the phenotype of p23 (show CDK5R1 ELISA Kits)-null embryos is strikingly similar to that of embryos lacking the glucocorticoid receptor, a paradigmatic Hsp90 (show HSP90 ELISA Kits)-p23 (show CDK5R1 ELISA Kits) client protein, we investigated glucocorticoid signaling.

  2. REV-ERBalpha (show NR1D1 ELISA Kits) binds to the C-terminal portion and GR to the N-terminal portion of HSP90alpha and HSP90beta (show HSP90AB1 ELISA Kits), a chaperone responsible for the activation of proteins to ensure survival of a cell.

  3. Phospho-AMPK (show PRKAA1 ELISA Kits) is a molecular switch able to cooperate with glucocorticoid receptors and Ppar-alpha (show PPARA ELISA Kits) at the chromatin level, a novel adaptation mechanism to prolonged fasting.

  4. GR signaling decreases NRF2 (show NFE2L2 ELISA Kits) transcriptional activation through reducing the NRF2 (show NFE2L2 ELISA Kits)-dependent histone acetylation. Consistent with these observations, GR signaling blocked NRF2 (show NFE2L2 ELISA Kits)-mediated cytoprotection from oxidative stress.

  5. GRbeta antagonizes the GC-induced signaling during fasting via GRalpha and the PPARalpha (show PPARA ELISA Kits)-FGF21 (show FGF21 ELISA Kits) axis that reduces fat burning. Furthermore, hepatic GRbeta increases inflammation, which leads to hepatic lipid accumulation.

  6. liver-specific deletion of GR resulted in a significant increase in mRNA expression of key genes involved in gluconeogenesis and glycogen (show GYS1 ELISA Kits) metabolism in kidney tissue, indicating a compensatory mechanism to maintain glucose homeostasis. Liver GRKO mice demonstrated decreased fat mass and liver glycogen (show GYS1 ELISA Kits) content compared with WT mice administered dexamethasone for 2 weeks.

  7. These results established a novel role for GR and KLF13 (show KLF13 ELISA Kits) signaling in adult cardiomyocytes with potential clinical implications for the prevention of cardiotoxicity induced heart failure.

  8. miR (show MLXIP ELISA Kits)-433 helps maintain circadian rhythm in osteoblasts by regulating sensitivity to glucocorticoid receptor signaling.

  9. this study shows that Nr3c1 regulates the formation of memory-precursor CD8 (show CD8A ELISA Kits)+ T cell fates

  10. Chronic subordinate colony housing (chronic psychosocial stressed) mice showed decreased GR mRNA and cytoplasmic protein levels compared with single-housed control mice.

Guinea Pig Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. The guinea pig GR-specific mutations within the H1-H3 loop confer global changes within the GR-Hsp90 (show HSP90 ELISA Kits) complex that favor FKBP51 (show FKBP5 ELISA Kits) repression over FKBP52 (show FKBP4 ELISA Kits) potentiation.

Human Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. NR3C1 polymorphism is associated with metabolic syndrome.

  2. The data of this study show a significant increase in DNA methylation (show HELLS ELISA Kits) of NR3C1 in peripheral blood mononuclear cells of major depressive disorder patients.

  3. Polymorphisms of the glucocorticoid receptor gene influenced both the basal state of the hypothalamus-pituitary-adrenal axis as well as self-perceived stress. The mineralocorticoid receptor (show NR3C2 ELISA Kits) gene only associated with self-perceived stress and 5-HTT (show SLC6A4 ELISA Kits) only with the cortisol awakening response.

  4. Findings suggest that posttraumatic stress disorder (PTSD) phenotypes may be characterized by differences in intracellular signaling transduction processes. The associations of expression of GRalpha and FKBP5 (show FKBP5 ELISA Kits) in the glucocorticoid (GC) high-sensitive PTSD subgroup may thereby reflect physiological adaptation to preserve immune-relevant GC signaling.

  5. results reveal that liganded GR spatiotemporally controls ANGPTL4 (show ANGPTL4 ELISA Kits) transcription in a chromosomal context.

  6. NR3C1 is a bona fide target of miR (show MLXIP ELISA Kits)-124 in acute lymphoblastic leukemia.

  7. Numerous direct transcriptional targets of GR exist in airway smooth muscle. Genes with inducible GR occupancy included IRS2 (show IRS2 ELISA Kits), APPL2 (show APLP2 ELISA Kits), RAMP1 (show RAMP1 ELISA Kits), and MFGE8 (show MFGE8 ELISA Kits). GR occupancy occurred in the absence of supplemental ligand, including robust GR binding peaks within the IL11 (show IL11 ELISA Kits) and LIF (show LIF ELISA Kits) loci.

  8. These results demonstrate that BCLI, N363S and ER22/23EK polymorphisms of NR3C1 do not play a pathogenetic role for Adrenal Incidentalomas.

  9. NR3C1 is a haploinsufficient tumor suppressor in a subset of blastic plasmacytoid dendritic cell neoplasms (BPDCN).

  10. Glucocorticoid receptor polymorphisms are associated with altered glucocorticoid sensitivity and changes in glucose homeostasis, and other metabolic parameters (Review)

Pig (Porcine) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. These results indicate that myostatin (show MSTN ELISA Kits) mediates maternal low protein diet-induced growth retardation, through epigenetic regulation involving FoxO3 (show FOXO3 ELISA Kits) and glucocorticoid receptor binding to its promoter.

  2. Data indicate that higher hepatic glucocorticoid receptor (GR) expression in EHL piglets attributes mainly to the enhanced transcription of GR promoter 1-9/10 from breed-specific interaction of p53 (show TP53 ELISA Kits) and specificity protein 1 (Sp1 (show SP1 ELISA Kits)).

  3. Tissue specificities, gene expression and induction responsiveness of the porcine NR3C1 gene.

  4. Cloning and dna sequence analysis of the upstream flanking region of the NR3C1 gene in the domestic pig.

  5. Effects of age, weaning and/or social isolation on the expression of genes regulating glucocorticoid response [glucocorticoid receptor).

Cow (Bovine) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. Glucocorticoid Receptor protein expression in granulosa cells was higher in cysts from animals with spontaneous cystic ovarian disease and adrenocorticotropic hormone-induced cystic ovarian disease than in tertiary follicles from control animals.

  2. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 ELISA Kits) and PTGS2 (show PTGS2 ELISA Kits), and decreased the expression of SOD2 (show SOD2 ELISA Kits), GPX3 (show GPX3 ELISA Kits), DAB2 (show DAB2 ELISA Kits), and NR3C1. TNF (show TNF ELISA Kits) and IL6 (show IL6 ELISA Kits) levels were also decreased while those of NAMPT (show NAMPT ELISA Kits) were unaffected.

  3. Bayesian image analysis of dexamethasone and shear stress-induced glucocorticoid receptor intracellular movement

  4. investigation of gene expression for GR, 11HSD1, and 11HSD2 (show HSD11B2 ELISA Kits) in granulosa cells and theca interna layers during follicular maturation and atresia: expression of GR was largely unchanged during follicular maturation

Rainbow Trout (Oncorhynchus mykiss) Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) interaction partners

  1. The E domain of the trout receptors are not involved in the nucleocytoplasmic localization of naive trout GRs (show GARS ELISA Kits), but the A/B domain, especially if linked to the corresponding trout CD region, plays a pivotal role in the cellular distribution pattern.

Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1) Antigen Profile

Antigen Summary

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).

Alternative names and synonyms associated with Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1)

  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1) Elisa Kit
  • nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (nr3c1) Elisa Kit
  • nuclear receptor subfamily 3, group C, member 1 (NR3C1) Elisa Kit
  • glucocorticoid receptor (LOC100302444) Elisa Kit
  • nuclear receptor subfamily 3, group C, member 1 (Nr3c1) Elisa Kit
  • GCCR Elisa Kit
  • GCL Elisa Kit
  • GCR Elisa Kit
  • gr Elisa Kit
  • GR-A Elisa Kit
  • GRL Elisa Kit
  • Grl-1 Elisa Kit
  • Grl1 Elisa Kit
  • LOC100302444 Elisa Kit
  • NO Elisa Kit
  • nr3c1 Elisa Kit
  • xGR Elisa Kit
  • zgc:113038 Elisa Kit

Protein level used designations for NR3C1

glucocorticoid receptor , nuclear receptor subfamily 3, group C, member 1 , glucocorticoid receptor 1 , GR , nuclear receptor subfamily 3 group C member 1 , glucocorticoid nuclear receptor variant 1 , glucocorticoid receptor alpha , glucocorticoid receptor variant P , glucocorticoid receptor variant beta , glucocorticoid receptor variant gamma

GENE ID SPECIES
100061217 Equus caballus
549721 Xenopus (Silurana) tropicalis
553740 Danio rerio
692348 Felis catus
100302444 Oryzias latipes
24413 Rattus norvegicus
14815 Mus musculus
100135583 Cavia porcellus
2908 Homo sapiens
100008890 Oryctolagus cuniculus
443412 Ovis aries
396740 Sus scrofa
281946 Bos taurus
478047 Canis lupus familiaris
416343 Gallus gallus
100136786 Oncorhynchus mykiss
100173284 Pongo abelii
100394916 Callithrix jacchus
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