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Human NME3 Protein expressed in Escherichia coli (E. coli) - ABIN667337
Martinez, Venturelli, Perrotti, Veronese, Kastury, Druck, Huebner, Calabretta: Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family. in Cancer research 1997
Show all 2 references for ABIN667337
Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer.
Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility.
NME3 protein interacts with RHO signaling cascades to impair sperm motility through hyperactivation of SMOK, the wild-type form of the responder.
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
, NDP kinase 3
, NDP kinase C
, non-metastatic cells 3, protein expressed in
, nucleoside diphosphate kinase 3
, nucleoside diphosphate kinase C
, expressed in non-metastatic cells 3
, nucleoside diphosphate kinase DR-nm23