anti-Interleukin 1 alpha (IL1A) antibody pair
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- Target See all IL1A products
- IL1A (Interleukin 1 alpha (IL1A))
- Reactivity
- Mouse
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Host
- Rabbit
- Clonality
- Polyclonal
- Method Type
- Sandwich ELISA
- Detection Range
- 15.6-2000 pg/mL
- Minimum Detection Limit
- 15.6 pg/mL
- Application
- ELISA
- Specificity
- Detects mouse IL-1alpha.
- No Cross-Reactivity
- Human
- Cross-Reactivity (Details)
- Does not detect human IL-1alpha or mouse IL-1beta.
- Sensitivity
- 10 pg/mL
- Components
- 1 vial standard protein (1μg) (lyophilized) [STD] 1 vial coating antibody (120μg) [COAT] 1 vial detection antibody (30μg) [DET] 1 vial streptavidin-HRP (10μg) (lyophilized) [STREP]
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IL1A & IL1R2 Protein Protein Interaction Antibody Pair
PLA Reactivity: Human PLA unconjugated Host: Rabbit, Mouse
IL1A (Human) Matched Antibody PairELISA Reactivity: Human ELISA unconjugated Host: Mouse
IL1A (Human) Matched Antibody PairELISA Reactivity: Human ELISA unconjugated Host: Rabbit, Mouse
IL1A (Human) Matched Antibody PairELISA Reactivity: Human ELISA unconjugated Host: Rabbit, Mouse
IL1A (Human) IP-WB Antibody PairIP Reactivity: Human IP unconjugated Host: Rabbit, Mouse
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- Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Storage
- -20 °C
- Storage Comment
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Short Term Storage: -20°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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- Target
- IL1A (Interleukin 1 alpha (IL1A))
- Alternative Name
- IL-1alpha (IL1A Products)
- Synonyms
- IL-1A Matched Antibody Pair, IL1 Matched Antibody Pair, IL1-ALPHA Matched Antibody Pair, IL1F1 Matched Antibody Pair, IL-6 Matched Antibody Pair, Il-1a Matched Antibody Pair, IL-1 alpha Matched Antibody Pair, IL-1alpha Matched Antibody Pair, L1A Matched Antibody Pair, interleukin 1 alpha Matched Antibody Pair, interleukin 6 Matched Antibody Pair, IL1A Matched Antibody Pair, IL6 Matched Antibody Pair, Il1a Matched Antibody Pair
- Background
- The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.
- UniProt
- P01582
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