Mitochondrial Ribosomal Protein L2 (MRPL2) (N-Term) Peptide
MRPL2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MRPL2 products
- MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GGGHKQRYRM IDFLRFRPEE TKSGPFEEKV IQVRYDPCRS ADIALVAGGS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MRPL2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))
- Synonyms
- MRP-L14 Peptide, RPML14 Peptide, CGI-22 Peptide, Rpml14 Peptide, mitochondrial ribosomal protein L2 Peptide, MRPL2 Peptide, Mrpl2 Peptide
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q.
Alias Symbols: MRP-L14, RPML14
Protein Size: 305 - Molecular Weight
- 33 kDa
- Gene ID
- 51069
- NCBI Accession
- NM_015950, NP_057034
- UniProt
- Q5T653
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