Mitochondrial Ribosomal Protein L18 (MRPL18) (N-Term) Peptide
MRPL18
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MRPL18 products
- MRPL18 (Mitochondrial Ribosomal Protein L18 (MRPL18))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RNPGCRFAAL STSSEPAAKP EVDPVENEAV APEFTNRNPR NLELLSVARK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MRPL18 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRPL18 (Mitochondrial Ribosomal Protein L18 (MRPL18))
- Synonyms
- L18mt Peptide, MRP-L18 Peptide, 1010001C05Rik Peptide, C79879 Peptide, HSPC071 Peptide, mitochondrial ribosomal protein L18 Peptide, MRPL18 Peptide, Mrpl18 Peptide
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.
Alias Symbols: L18mt, MRP-L18
Protein Size: 180 - Molecular Weight
- 20 kDa
- Gene ID
- 29074
- NCBI Accession
- NM_014161, NP_054880
- UniProt
- Q9H0U6
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