Anoctamin 1, Calcium Activated Chloride Channel (ANO1) (C-Term) Peptide
ANO1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ANO1 products
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LMVELFMREE QDKQQLLETW MEKERQKDEP PCNHHNTKAC PDSLGSPAPS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ANO1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
- Synonyms
- DOG1 Peptide, ORAOV2 Peptide, TAOS2 Peptide, TMEM16A Peptide, Tmem16a Peptide, anoctamin 1 Peptide, anoctamin 1, calcium activated chloride channel Peptide, Ano1 Peptide, ANO1 Peptide
- Background
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ANO1 is a calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. It is required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. It acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Alias Symbols: ANO1,DOG1,ORAOV2,TAOS2,TMEM16A,
Protein Size: 986 - Gene ID
- 55107
- NCBI Accession
- NP_060513
- UniProt
- Q5XXA6
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