X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (Middle Region) Peptide
XRCC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all XRCC3 products
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- HQQKERFPTQ HQRLSLGCPV LDALLRGGLP LDGITELAGR SSAGKTQLAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- XRCC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- Synonyms
- CMM6 Peptide, 4432412E01Rik Peptide, AI182522 Peptide, AW537713 Peptide, MGC69118 Peptide, im:7142103 Peptide, zgc:101608 Peptide, si:dkey-11b8.1 Peptide, xrcc3 Peptide, XRCC3 Peptide, X-ray repair cross complementing 3 Peptide, X-ray repair complementing defective repair in Chinese hamster cells 3 Peptide, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog Peptide, XRCC3 Peptide, Xrcc3 Peptide, xrcc3.L Peptide, xrcc3 Peptide
- Background
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This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Alias Symbols: CMM6
Protein Size: 346 - Gene ID
- 7517
- NCBI Accession
- NM_001100118, NP_001093588
- UniProt
- O43542
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