Timeless Homolog (TIMELESS) Peptide
Quick Overview for Timeless Homolog (TIMELESS) Peptide (ABIN937729)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- EEEDAVGKEP LKAAPKKRQL LDSDEEQEED EGRNRAPELG APGIQKKKRY
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TIMELESS antibody,
Alternative Names: TIMELESS control peptide, TIMELESS antibody Blocking Peptide, Anti-TIMELESS Blocking Peptide, timeless homolog, Drosophila Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TIMELESS (Timeless Homolog (TIMELESS))
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Background
- The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
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Molecular Weight
- 139 kDa
Target
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