Timeless Homolog (TIMELESS) Peptide
TIMELESS
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985093
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Timeless Homolog (TIMELESS) Peptide (ABIN985093)
Target
TIMELESS
(Timeless Homolog (TIMELESS))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-TIMELESS antibody (Catalog #: ARP38404_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeated freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- TIMELESS (Timeless Homolog (TIMELESS))
-
Background
-
The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Alias Symbols: TIM, TIM1, hTIM
Protein Interaction Partner: CRY1,PER1,PER2,TIPIN,ATRIP,CHEK1,CLSPN,CRY2,Clock,PCNA,Per1,Per2,TIPIN,per
Protein Size: 1208 -
Molecular Weight
- 139 kDa
-
Gene ID
- 8914
-
NCBI Accession
- NM_003920, NP_003911
-
UniProt
- Q9UNS1
Target
-
You are here:
