E3 ubiquitin-protein ligase RAD18 (RAD18) Peptide
RAD18
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940003
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for E3 ubiquitin-protein ligase RAD18 (RAD18) Peptide (ABIN940003)
Target
RAD18
(E3 ubiquitin-protein ligase RAD18 (RAD18))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KQVTKVDCPV CGVNIPESHI NKHLDSCLSR EEKKESLRSS VHKRKPLPKT
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RAD18 antibody,
Alternative Names: RAD18 control peptide, RAD18 antibody Blocking Peptide, Anti-RAD18 Blocking Peptide, Rad18 Homolog Blocking Peptide, RNF73 Blocking Peptide, RAD18, RAD-18, RAD 18, RAD-18 Blocking Peptide, RAD 18 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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Background
- RAD18 is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, RAD18 is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
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Molecular Weight
- 56 kDa
Target
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