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Angiomotin (AMOT) (N-Term) Peptide

AMOT Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973179
  • Target See all Angiomotin (AMOT) products
    Angiomotin (AMOT)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-AMOT antibody (Catalog #: ARP34660_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Angiomotin (AMOT)
    Synonyms
    C81439 Peptide, CAG-2 Peptide, D0Kist1 Peptide, E230009N18Rik Peptide, Sii6 Peptide, mKIAA1071 Peptide, RGD1564027 Peptide, si:dkey-13f9.6 Peptide, wu:fj21a07 Peptide, angiomotin Peptide, microRNA 4329 Peptide, AMOT Peptide, Amot Peptide, MIR4329 Peptide, amot Peptide
    Background
    AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Alias Symbols: KIAA1071

    Protein Interaction Partner: MAGI1,PLG,AMOTL1,BAG3,DLG1,DYNLL1,DYNLL2,FOXK1,FOXK2,LIN7A,LIN7C,LONP2,MLH1,MPDZ,MPP5,MPP7,NEDD4L,NF2,NIN,SCLT1,UIMC1,USP11,USP42,YAP1

    Protein Size: 675
    Molecular Weight
    73 kDa
    Gene ID
    154796
    NCBI Accession
    NM_133265, NP_573572
    UniProt
    Q4VCS5
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