Angiomotin (AMOT) (N-Term) Peptide
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- Target See all Angiomotin (AMOT) products
- Angiomotin (AMOT)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AMOT antibody (Catalog #: ARP34660_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Angiomotin (AMOT)
- Synonyms
- C81439 Peptide, CAG-2 Peptide, D0Kist1 Peptide, E230009N18Rik Peptide, Sii6 Peptide, mKIAA1071 Peptide, RGD1564027 Peptide, si:dkey-13f9.6 Peptide, wu:fj21a07 Peptide, angiomotin Peptide, microRNA 4329 Peptide, AMOT Peptide, Amot Peptide, MIR4329 Peptide, amot Peptide
- Background
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AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: KIAA1071
Protein Interaction Partner: MAGI1,PLG,AMOTL1,BAG3,DLG1,DYNLL1,DYNLL2,FOXK1,FOXK2,LIN7A,LIN7C,LONP2,MLH1,MPDZ,MPP5,MPP7,NEDD4L,NF2,NIN,SCLT1,UIMC1,USP11,USP42,YAP1
Protein Size: 675 - Molecular Weight
- 73 kDa
- Gene ID
- 154796
- NCBI Accession
- NM_133265, NP_573572
- UniProt
- Q4VCS5
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