Amphiregulin (AREG) (Middle Region) Peptide
AREG
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Amphiregulin (AREG) products
- Amphiregulin (AREG)
- Protein Region
- Middle Region
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AREG Antibody(ARP30233_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Amphiregulin (AREG)
- Synonyms
- AR Peptide, CRDGF Peptide, SDGF Peptide, Sdgf Peptide, AREG Peptide, AREGB Peptide, AREG/SDGF Peptide, amphiregulin Peptide, AREG Peptide, Areg Peptide
- Background
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The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.
Alias Symbols: AR, AREGB, CRDGF, MGC13647, SDGF
Protein Interaction Partner: CCND3,EGFR,MMP9,UBQLN4,WT1,EGFR
Protein Size: 252 - Molecular Weight
- 28 kDa
- Gene ID
- 374
- NCBI Accession
- NM_001657, NP_001648
- UniProt
- P15514
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