Bromodomain Containing 4 (BRD4) Peptide
BRD4
Reactivity: Human
Host: Synthetic
BP, WB, IF, ChIP
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- Target See all BRD4 products
- BRD4 (Bromodomain Containing 4 (BRD4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BRD4 antibody (Catalog #: ARP39076_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BRD4 (Bromodomain Containing 4 (BRD4))
- Synonyms
- brd4-b Peptide, BRD4 Peptide, fb18g03 Peptide, wu:fb18g03 Peptide, CAP Peptide, HUNK1 Peptide, HUNKI Peptide, MCAP Peptide, Brd5 Peptide, WI-11513 Peptide, bromodomain containing 4 L homeolog Peptide, bromodomain containing 4 Peptide, bromodomain-containing protein 4 Peptide, brd4.L Peptide, BRD4 Peptide, brd4 Peptide, LOC100409351 Peptide, Brd4 Peptide
- Background
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BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting.The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Alias Symbols: CAP, HUNKI, MCAP, HUNK1
Protein Interaction Partner: E2,C7orf25,CHFR,CLDN1,PRPF40A,RFC1,RFC4,CCNT1,CCNT2,CDK9,HEXIM1,HIST2H3C,HIST2H4A,HIST4H4,MED12,MED14,MED17,MED24,RFC1,RFC2,RFC3,RFC4,RFC5,SIPA1
Protein Size: 722 - Molecular Weight
- 80 kDa
- Gene ID
- 23476
- NCBI Accession
- NM_014299, NP_055114
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