Collagen, Type VI, alpha 1 (COL6A1) (Middle Region) Peptide
COL6A1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all COL6A1 products
- COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COL6A1 antibody (Catalog #: ARP45803_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))
- Synonyms
- CBR Peptide, SDR21C1 Peptide, hCBR1 Peptide, OPLL Peptide, AI747156 Peptide, Col6a-1 Peptide, RGD1565398 Peptide, COL6A1 Peptide, carbonyl reductase 1 Peptide, collagen type VI alpha 1 chain Peptide, collagen, type VI, alpha 1 Peptide, collagen, type VI, alpha 1 L homeolog Peptide, collagen type VI alpha 3 chain Peptide, collagen alpha-1(VI) chain Peptide, CBR1 Peptide, COL6A1 Peptide, Col6a1 Peptide, col6a1.L Peptide, COL6A3 Peptide, col6a1 Peptide, LOC100623720 Peptide
- Background
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COL6A1 is a collagen VI which acts as a cell-binding protein.Defects in COL6A1 are a cause of Bethlem myopathy (BM).The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. This gene, which encodes a neural small non-messenger RNA, is a member of the family of interspersed repetitive DNA, and its product represents an example of a primate tissue-specific RNA polymerase III transcript. The RNA sequence is divided into three domains: a 5' portion homologous to the Alu Lm, a central adenosine-rich region, and the terminal 43-nt nonrepetitive domain. It is believed that this gene was retropositionally generated and recruited into a function regulating dendritic protein biosynthesis. At least two pseudogenes of this gene have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-200 AF020057.2 4262-4461
Alias Symbols: OPLL
Protein Interaction Partner: COL2A1,FGF7,LAMB1,LGALS3BP,DCN,MAG
Protein Size: 1028 - Molecular Weight
- 106 kDa
- Gene ID
- 1291
- NCBI Accession
- NM_001848, NP_001839
- UniProt
- P12109
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