CREB Binding Protein (CREBBP) (N-Term) Peptide
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- Target See all CBP (CREBBP) products
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CREBBP antibody (Catalog #: ARP43609_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- Synonyms
- CBP Peptide, KAT3A Peptide, RSTS Peptide, AW558298 Peptide, CBP/p300 Peptide, p300/CBP Peptide, RTS Peptide, cbp Peptide, crebbp Peptide, kat3a Peptide, rsts Peptide, hmm291030 Peptide, Nejire Peptide, CREB binding protein Peptide, CREB binding protein L homeolog Peptide, histone acetyltransferase p300 Peptide, CREBBP Peptide, Crebbp Peptide, crebbp.L Peptide, LOC100123220 Peptide
- Background
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CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.
Alias Symbols: CBP, KAT3A, RSTS, RTS
Protein Interaction Partner: EGR1,AIRE,BNIP3L,BRCA1,CCND1,CDKN1A,CDKN1A,CREB1,CREB1,CTBP1,DAXX,EGR1,H3F3A,HCVgp1,HNF1A,HNF4A,HSF1,HTT,HTT,ICAM1,IRF3,MAF,NAP1L1,NCOA3,NCOA3,NCOA3,PAX5,RELA,RELA,SMAD2,SMAD2,SMAD3,STAT1,STAT1,STAT3,TACC2,TCF12,TCF12,TFF1,TNFSF10,TP53,ACTA2,ACVR1,AIRE,ALX1,AP1B1,AR,ATF1,BCL3,BRCA1,CALCOCO1,CAMK4,CARM1,CDC25B,CDH2,CDK5RAP3,CDX2,CEBPA,CEBPB,CEBPD,CENPJ,CHUK,CITED1,CITED2,CNOT3,CREB1,CREBBP,CREM,CRX,CSK,CSNK2A1,CSNK2A2,CTBP1,CTNNB1,CUX1,DACH1,DAXX,DDX5,E2F1,E2F5,EBF1,EGR1,EID3,EIF2B1,ELF3,ELK1,EP300,ESR1,ETS1,ETS2,EWSR1,FGFR1,FHL2,FOXM1,FOXO1,FOXO4,GABPA,GAK,GATA1,GCM1,GLI3,GMEB1,GMEB2,GTF2B,H3F3B,HDAC1,HDAC3,HIF1A,HIPK2,HLF,HMGA1,HNF1A,HNF1B,HNF4A,HOXA10,HOXA11,HOXA9,HOXB1,HOXB2,HOXB3,HOXB4,HOXB6,HOXB7,HOXB9,HOXD10,HOXD4,HSF1,HTT,IKBKG,IRF3,IRF7,JDP2,JUN,KAT2A,KAT2B,KAT5,KHDRBS1,KLF13,KLF4,KLF5,KPNA2,MAF,MAFG,MAML1,MAML2,MBD2,MDC1,MDM2,MECOM,MGMT,MLL,MSH2,MSH6,MSX1,MYB,MYBL1,MYBL2,MYC,MYOD1,N4BP2,NAP1L1,NCOA1,NCOA2,NCOA3,NCOA6,NEUROG1,NFATC2,NFATC4,NFE2,NFE2L2,NFIA,NFIC,NKX2-1,NLK,NPAS2,NPAT,NR3C1,NUP98,ONECUT1,PAX5,PCMT1,PELP1,PHOX2A,PIAS1,PML,POLR2A,POU1F1,POU2F3,PRKCD,PROX1,PTMA,RBBP4,RBCK1,RELA,RPS6KA1,RPS6KA3,RPS6KA5,RXRG,SERTAD1,SERTAD2,SERTAD3,SH3GL1,SMAD2,SMAD3,SMAD4,SND1,SNIP1,SOX9,SPI1,SPIB,SRCAP,SREBF1,SREBF2,SRF,SS18L1,STAT1,STAT2,STAT3,STAT4,STAT6,SUV39H1,TACC2,TCF12,TCF3,TDG,TGS1,THRA,TP53,TP73,TRERF1,TRIP10,TRIP4,UBTF,VDR,WT1,YWHAH,ZBTB17,ZBTB2,ZNF639,ABCA1,AIRE,AR,ATF1,ATF2,ATF4,BRCA1,CCNC,CDK8,CITED1,CITED2,CREB1,CSK,CSNK2A1,CSNK2A2,CTNNB1,CUX1,DDX5,E2F1,E2F3,EBF1,EGR1,EP300,ESR1,EWSR1,FOS,FOXO1,FOXO4,GATA1,GLI3,GTF2B,HIF1A,HIPK2,HIST3H3,HIST4H4,HNF1A,HNF4A,HOXB7,HTT,ING1,IRF3,JUN,KAT2B,KHDRBS1,KLF1,KLF13,KLF4,KLF5,MAF,MAML1,MECOM,MED21,MGMT,MLL,MSX1,MYB,MYBL2,MYOD1,N4BP2,NCOA1,NCOA3,NCOA6,NEUROG1,NFATC2,NFATC4,NFE2,NFE2L2,NKX2-1,NPAS2,NR3C1,NUP98,ONECUT1,PELP1,PHOX2A,PIAS3,PML,POLR2A,PPARG,PPARGC1A,PTMA,RBBP4,RBBP7,RELA,RPA2,RPS6KA2,RPS6KA3,SERTAD1,SMAD1,SMARCA4,SMARCB1,SNIP1,SREBF1,SREBF2,SRF,SS18L1,STAT1,STAT2,STAT3,STAT6,TCF3,TDG,TGS1,TP53,TRERF1,TRIP4,XRCC6
Protein Size: 2404 - Molecular Weight
- 261 kDa
- Gene ID
- 1387
- NCBI Accession
- NM_001079846, NP_001073315
- UniProt
- Q4LE28
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