Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Peptide
CYP2E1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CYP2E1 products
- CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CYP2E1 antibody (Catalog #: ARP41424_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
- Synonyms
- CYP2E1 Peptide, CYP2E Peptide, CYPIIE1 Peptide, CPE1 Peptide, P450-J Peptide, P450C2E Peptide, Cyp2e Peptide, cytochrome P450, family 2, subfamily E, polypeptide 1 Peptide, cytochrome P450 2E1 Peptide, cytochrome P450 2E1-like Peptide, cytochrome P450 family 2 subfamily E member 1 Peptide, cytochrome P450, family 2, subfamily e, polypeptide 1 Peptide, CYP2E1 Peptide, PTRG_07411 Peptide, LOC100342572 Peptide, LOC100727914 Peptide, LOC101843716 Peptide, Cyp2e1 Peptide
- Background
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CYP2E1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
Alias Symbols: CPE1, CYP2E, P450-J, P450C2E
Protein Interaction Partner: POR,FANCG,POR
Protein Size: 493 - Molecular Weight
- 54 kDa
- Gene ID
- 1571
- NCBI Accession
- NM_000773, NP_000764
- UniProt
- P05181
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