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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23) Peptide

DDX23 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975678
  • Target See all DDX23 products
    DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DDX23 antibody (Catalog #: ARP36376_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))
    Synonyms
    PRPF28 Peptide, SNRNP100 Peptide, U5-100K Peptide, U5-100KD Peptide, prp28 Peptide, wu:fi39b12 Peptide, zgc:63742 Peptide, 3110082M05Rik Peptide, 4921506D17Rik Peptide, DEAD-box helicase 23 Peptide, U5 snRNP 100 kD protein Peptide, DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 Peptide, DDX23 Peptide, cgd3_3690 Peptide, Chro.30417 Peptide, PY04051 Peptide, ddx23 Peptide, Ddx23 Peptide
    Background
    DDX23 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex, it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

    Alias Symbols: prp28, PRPF28, U5-100K, U5-100KD

    Protein Interaction Partner: CD2BP2,MEPCE,OTUB1,PRPF4,RNPS1,USP39

    Protein Size: 820
    Molecular Weight
    90 kDa
    Gene ID
    9416
    NCBI Accession
    NM_004818, NP_004809
    UniProt
    Q9BUQ8
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