Der1-Like Domain Family, Member 3 (DERL3) Peptide
DERL3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Derlin-3 (DERL3) products
- Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DERL3 antibody (Catalog #: ARP44443_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Derlin-3 (DERL3) (Der1-Like Domain Family, Member 3 (DERL3))
- Synonyms
- 1810006I20Rik Peptide, 1810063P04Rik Peptide, IZP6 Peptide, derlin-3 Peptide, zgc:63991 Peptide, C22orf14 Peptide, LLN2 Peptide, derlin 3 Peptide, Der1-like domain family, member 3 Peptide, DERL3 Peptide, Derl3 Peptide, derl3 Peptide
- Background
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DERL3 belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL3 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).[supplied by OMIM].
Alias Symbols: C22orf14, IZP6, MGC71803, LLN2, derlin-3
Protein Interaction Partner: MFI2,SERPINA1,AMFR
Protein Size: 235 - Molecular Weight
- 27 kDa
- Gene ID
- 91319
- NCBI Accession
- NM_001002862, NP_001002862
- UniProt
- Q96Q80
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