Fragile Histidine Triad (FHIT) (Middle Region) Peptide
FHIT
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FHIT products
- FHIT (Fragile Histidine Triad (FHIT))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VHVLPRKAGD FHRNDSIYEE LQKHDKEDFP ASWRSEEEMA AEAAALRVYF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FHIT Antibody(ARP51169_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FHIT (Fragile Histidine Triad (FHIT))
- Synonyms
- AP3Aase Peptide, FRA3B Peptide, FHIT Peptide, zgc:73176 Peptide, AW045638 Peptide, Fra14A2 Peptide, LOC100223655 Peptide, fragile histidine triad Peptide, fragile histidine triad gene Peptide, fragile histidine triad protein Peptide, fragile histidine triad L homeolog Peptide, FHIT Peptide, Fhit Peptide, fhit Peptide, PY07476 Peptide, fhit.L Peptide
- Background
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This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: AP3Aase, FRA3B
Protein Interaction Partner: FDXR,FHIT,GSN,HSPD1,SRC,UBE2I,FHIT,UBE2I
Protein Size: 147 - Molecular Weight
- 17 kDa
- Gene ID
- 2272
- NCBI Accession
- NM_002012, NP_002003
- UniProt
- P49789
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