Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R) (N-Term) Peptide
MC2R
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MC2R products
- MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LRNMGYLKPR GSFETTADDI IDSLFVLSLL GSIFSLSVIA ADRYITIFHA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MC2R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))
- Synonyms
- ACTHR Peptide, ACTH-R Peptide, MC2-R Peptide, MC2R Peptide, MC2 Peptide, melanocortin 2 receptor Peptide, MC2R Peptide, Mc2r Peptide, mc2r Peptide
- Background
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MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
Alias Symbols: ACTHR, MGC125798
Protein Interaction Partner: ASIP,POMC
Protein Size: 297 - Molecular Weight
- 33 kDa
- Gene ID
- 4158
- NCBI Accession
- NM_000529, NP_000520
- UniProt
- Q01718
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