Minichromosome Maintenance Complex Component 3 (MCM3) Peptide
MCM3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all MCM3 products
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MCM3 antibody (Catalog #: ARP36644_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
- Synonyms
- HCC5 Peptide, P1-MCM3 Peptide, P1.h Peptide, RLFB Peptide, AL033361 Peptide, C80350 Peptide, Mcmd Peptide, P1 Peptide, p1.m Peptide, cb32 Peptide, chunp6867 Peptide, wu:fa26g03 Peptide, CG4206 Peptide, DmMCM3 Peptide, DmMcm3 Peptide, DmeMCM3 Peptide, Dmel\\CG4206 Peptide, MCM3 Peptide, McM3 Peptide, Mcp-PCR2 Peptide, PCR2 Peptide, dMCM3 Peptide, xmcm3 Peptide, minichromosome maintenance complex component 3 Peptide, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) Peptide, Minichromosome maintenance 3 Peptide, minichromosome maintenance complex component 3 L homeolog Peptide, MCM complex subunit Mcm3 Peptide, MCM3 Peptide, mcm3 Peptide, Mcm3 Peptide, mcm3.L Peptide
- Background
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MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HCC5, MGC1157, P1-MCM3, P1.h, RLFB
Protein Interaction Partner: MCM2,MCM2,MCM5,MCM5,MCM7,MCM7,CDC45,CDC5L,CDC6,CDC7,CDK2,DBF4,HAUS1,MCM10,MCM2,MCM3AP,MCM4,MCM5,MCM6,MCM7,ORC2L,ORC4L,ORC5L,PLK1,POLR2A,PPP2R1A,PPP2R1B,RAD52,STAT1,SUPT16H,CDC45,CDC6,CDC7,DBF4,ENSA,MCM2,MCM3AP,MCM5,MCM7,ORC2L,ORC4L,ORC5L,PAK2,PMS2,PNKP,PTP4A3,RPA2,SNCG,WDR8
Protein Size: 808 - Molecular Weight
- 91 kDa
- Gene ID
- 4172
- NCBI Accession
- NM_002388, NP_002379
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