Mediator Complex Subunit 27 (MED27) (Middle Region) Peptide
MED27
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MED27 products
- MED27 (Mediator Complex Subunit 27 (MED27))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MED27 antibody (Catalog #: ARP33743_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED27 (Mediator Complex Subunit 27 (MED27))
- Synonyms
- CRAP34 Peptide, CRSP34 Peptide, CRSP8 Peptide, TRAP37 Peptide, CG1245 Peptide, Dmel\\CG1245 Peptide, Med27 Peptide, Trap37 Peptide, dCRSP34 Peptide, dCrsp34 Peptide, dTRAP37 Peptide, med27 Peptide, crsp8 Peptide, zgc:66302 Peptide, MED27 Peptide, DDBDRAFT_0216764 Peptide, DDBDRAFT_0266847 Peptide, DDB_0216764 Peptide, DDB_0266847 Peptide, 1500015J03Rik Peptide, 2310042P07Rik Peptide, AA682045 Peptide, Crsp8 Peptide, D2Ertd434e Peptide, RGD1564993 Peptide, DKFZp459I1912 Peptide, CRSP complex subunit 8-B Peptide, Xcrsp34 Peptide, crap34 Peptide, crsp34 Peptide, crsp8-B Peptide, med27-a Peptide, med27-b Peptide, trap37 Peptide, mediator complex subunit 27 Peptide, Mediator complex subunit 27 Peptide, cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa Peptide, hypothetical protein Peptide, mediator complex subunit 27 S homeolog Peptide, MED27 Peptide, med27 Peptide, crsp8 Peptide, Med27 Peptide, med27.S Peptide
- Background
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. MED27 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRAP34, CRSP34, CRSP8, MGC11274, TRAP37
Protein Interaction Partner: MED19,MED22,MED30,MED19,MED22,MED30,MED8,MED9,MED1,MED10,MED19,MED22,MED26,MED28,MED29,MED30,MED9
Protein Size: 311 - Molecular Weight
- 35 kDa
- Gene ID
- 9442
- NCBI Accession
- NM_004269, NP_004260
- UniProt
- Q6P2C8
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