Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7) (N-Term) Peptide
MPP7
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MPP7 products
- MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MPP7 antibody (Catalog #: ARP53247_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))
- Synonyms
- 1110068J02Rik Peptide, 2810038M04Rik Peptide, 5430426E14Rik Peptide, AI415104 Peptide, Gm955 Peptide, dlg3 Peptide, hmp Peptide, membrane palmitoylated protein 7 Peptide, membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) Peptide, membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) Peptide, MPP7 Peptide, Mpp7 Peptide, mpp7a Peptide
- Background
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MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).[supplied by OMIM].
Alias Symbols: FLJ32798, RP11-218D6.5
Protein Interaction Partner: AMOT
Protein Size: 576 - Molecular Weight
- 65 kDa
- Gene ID
- 143098
- NCBI Accession
- NM_173496, NP_775767
- UniProt
- Q5T2T1
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