phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) Peptide
PDE5A
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all PDE5A products
- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PDE5A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
- Synonyms
- CGB-PDE Peptide, CN5A Peptide, PDE5 Peptide, PDE5A2 Peptide, Cgbpde Peptide, Cn5n Peptide, Pde5 Peptide, Pde5a1 Peptide, PDE5A Peptide, pde5a Peptide, cgb-pde Peptide, cn5a Peptide, pde5 Peptide, pde5a1 Peptide, phosphodiesterase 5A Peptide, phosphodiesterase 5A, cGMP-specific Peptide, phosphodiesterase 5A S homeolog Peptide, phosphodiesterase 5A, cGMP-specific, b Peptide, PDE5A Peptide, Pde5a Peptide, pde5a.S Peptide, pde5ab Peptide, pde5a Peptide
- Background
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This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1
Protein Interaction Partner: CASP3,PRKG1
Protein Size: 823 - Molecular Weight
- 93 kDa
- Gene ID
- 8654
- NCBI Accession
- NM_033437, NP_246273
- UniProt
- O76074
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