Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4) Peptide

Details for Product No. ABIN981542, Supplier: Log in to see
Protein Name
  • AV005916
  • pyruvate dehydrogenase kinase, isozyme 4
  • pyruvate dehydrogenase kinase, isoenzyme 4
  • pdk4
  • LOC100230570
  • Pdk4
  • PDK4
Origin
Human
1
1
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Blocked Antibody anti-PDK4 antibody (Pyruvate Dehydrogenase Kinase, Isozyme 4) (N-Term) (ABIN2777592)
Characteristics This is a synthetic peptide designed for use in combination with anti-PDK4 antibody (Catalog #: ARP32787_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Alias Symbols: FLJ40832

Protein Interaction Partner: DLAT,PDHA1,PDK4,TRIM63

Protein Size: 411
Molecular Weight 46 kDa
Gene ID 5166
NCBI Accession NM_002612, NP_002603
UniProt Q16654
Research Area Signaling, Metabolism
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.