Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2) (Middle Region) Peptide
PLEKHG2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PLEKHG2 products
- PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DLTIPKHRHL LQAKNQEEKR LWIHCLQRLF FENHPASIPA KAKQVLLENS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PLEKHG2 Antibody(ARP59650_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))
- Synonyms
- ARHGEF42 Peptide, CLG Peptide, AI194308 Peptide, Clg Peptide, Cslg Peptide, pleckstrin homology and RhoGEF domain containing G2 Peptide, pleckstrin homology domain containing, family G (with RhoGef domain) member 2 Peptide, PLEKHG2 Peptide, Plekhg2 Peptide
- Background
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PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
Alias Symbols: CLG, DKFZp667J2325, FLJ00018, FLJ22458, FLJ38638, ARHGEF42
Protein Interaction Partner: CDC42,RAC1,RHOA,CDC42,RAC1,RHOA
Protein Size: 1344 - Molecular Weight
- 144 kDa
- Gene ID
- 64857
- NCBI Accession
- NM_022835, NP_073746
- UniProt
- Q9H7P9
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