PSMC3 Interacting Protein (PSMC3IP) (C-Term) Peptide
PSMC3IP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PSMC3IP products
- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMC3IP antibody (Catalog #: ARP47615_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
- Synonyms
- PSMC3IP Peptide, Arabidopsis Hop2 homolog Peptide, T6J4.9 Peptide, T6J4_9 Peptide, C79099 Peptide, GT198 Peptide, HOP2 Peptide, Tbpip Peptide, HUMGT198A Peptide, ODG3 Peptide, TBPIP Peptide, Gt198 Peptide, zgc:86785 Peptide, PSMC3 interacting protein Peptide, homologous-pairing protein 2 homolog Peptide, Homologous-pairing protein 2 homolog Peptide, homologous-pairing protein 2 homolog-like Peptide, Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) Peptide, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein Peptide, PSMC3 interacting protein L homeolog Peptide, PSMC3IP Peptide, LOC726449 Peptide, LOC100165513 Peptide, hop2 Peptide, psmc3ip Peptide, LOC100633854 Peptide, LOC100650062 Peptide, LOC789362 Peptide, AHP2 Peptide, Psmc3ip Peptide, psmc3ip.L Peptide
- Background
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PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
Alias Symbols: GT198, HOP2, TBPIP, ODG3, HUMGT198A
Protein Interaction Partner: AR,ESR2,NR3C1,PSMC3,PSMC3IP,RXRA,THRB,NR3C1
Protein Size: 205 - Molecular Weight
- 24 kDa
- Gene ID
- 29893
- NCBI Accession
- NM_013290, NP_037422
- UniProt
- Q9P2W1
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