RB1-Inducible Coiled-Coil 1 (RB1CC1) Peptide
RB1CC1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all FIP200 (RB1CC1) products
- FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RB1CC1 antibody (Catalog #: ARP50467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
- Synonyms
- DKFZp459E2330 Peptide, CC1 Peptide, FIP200 Peptide, 2900055E04Rik Peptide, 5930404L04Rik Peptide, Cc1 Peptide, LaXp180 Peptide, RB1 inducible coiled-coil 1 Peptide, RB1 inducible coiled-coil 1 L homeolog Peptide, RB1-inducible coiled-coil 1 Peptide, RB1CC1 Peptide, rb1cc1.L Peptide, rb1cc1 Peptide, Rb1cc1 Peptide
- Background
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RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.
Alias Symbols: CC1, DRAGOU14, FIP200
Protein Interaction Partner: PTK2,PTK2B,CDK19,DBNL,ERCC6L,MAP3K5,MOBKL3,PTK2,PTK2B,TRAF2
Protein Size: 1591 - Molecular Weight
- 183 kDa
- Gene ID
- 9821
- NCBI Accession
- NM_001083617, NP_001077086
- UniProt
- Q8TDY2
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