Retinoblastoma Binding Protein 8 (RBBP8) Peptide
RBBP8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Retinoblastoma Binding Protein 8 (RBBP8) products
- Retinoblastoma Binding Protein 8 (RBBP8)
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RBBP8 antibody (Catalog #: ARP50887_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Retinoblastoma Binding Protein 8 (RBBP8)
- Synonyms
- COM1 Peptide, CTIP Peptide, JWDS Peptide, RIM Peptide, SAE2 Peptide, SCKL2 Peptide, 9930104E21Rik Peptide, CtIP Peptide, RBBP-8 Peptide, RGD1308872 Peptide, RBBP8 Peptide, DKFZp469K0714 Peptide, RB binding protein 8, endonuclease Peptide, retinoblastoma binding protein 8, endonuclease Peptide, retinoblastoma binding protein 8 L homeolog Peptide, retinoblastoma binding protein 8 Peptide, RBBP8 Peptide, Rbbp8 Peptide, rbbp8.L Peptide, rbbp8 Peptide
- Background
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RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Alias Symbols: CTIP, RIM, JWDS, SAE2, SCKL2
Protein Interaction Partner: BRCA1,LMO2,LMO4,ATM,BARD1,BRCA1,C17orf28,CTBP1,FXR2,IKZF1,IKZF3,LIMS1,LMO2,LMO4,PCNA,PIN1,RB1,RBBP8,RBL1,RBL2,SIAH1,SIAH2,TGIF2,WDYHV1,ATM,BARD1,BRCA1,C17orf28,CTBP1,FXR2,IKZF1,LIMS1,LMO4,Lmo2,PIN1,PRKDC,RB1,RBBP8,RBL1,RBL2,SIAH1,SIAH2,WDYHV1
Protein Size: 867 - Molecular Weight
- 98 kDa
- Gene ID
- 5932
- NCBI Accession
- NM_203292, NP_976037
- UniProt
- A6NKN2
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