Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptide
RIPK3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RIPK3 products
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RIPK3 antibody (Catalog #: ARP32835_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- Synonyms
- RIPK3 Peptide, RIP3 Peptide, 2610528K09Rik Peptide, AW107945 Peptide, Rip3 Peptide, Hcyp2 Peptide, receptor interacting serine/threonine kinase 3 Peptide, receptor interacting serine/threonine kinase 3 S homeolog Peptide, receptor-interacting serine-threonine kinase 3 Peptide, RIPK3 Peptide, ripk3.S Peptide, Ripk3 Peptide
- Background
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RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RIP3
Protein Interaction Partner: RIPK1,TICAM1,TNFRSF1A,TRAF2,RIPK1,TICAM1,TNFRSF1A,TRAF2
Protein Size: 518 - Molecular Weight
- 57 kDa
- Gene ID
- 11035
- NCBI Accession
- NM_006871, NP_006862
- UniProt
- Q9Y572
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