Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2) (N-Term) Peptide
SLC1A2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all SLC1A2 products
- SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SLC1A2 antibody (Catalog #: ARP33840_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))
- Synonyms
- CG3159 Peptide, Dmel\\CG3159 Peptide, EAAT Peptide, dEAAT2 Peptide, dEaat2 Peptide, Eaat Peptide, GB16377 Peptide, EAAT2 Peptide, SLC1A2 Peptide, Eaat2 Peptide, Glt Peptide, Glt-1 Peptide, GLT-1 Peptide, 1700091C19Rik Peptide, 2900019G14Rik Peptide, AI159670 Peptide, GLT1 Peptide, MGLT1 Peptide, eaat2 Peptide, fj34b12 Peptide, slc1a2 Peptide, wu:fj34b12 Peptide, zgc:65897 Peptide, Excitatory amino acid transporter 2 Peptide, excitatory amino acid transporter 2 Peptide, solute carrier family 1 member 2 Peptide, solute carrier family 1 (glial high affinity glutamate transporter), member 2 Peptide, solute carrier family 1 (glial high affinity glutamate transporter), member 2b Peptide, Eaat2 Peptide, Eaat-2 Peptide, SLC1A2 Peptide, VDBG_06180 Peptide, EUBELI_01747 Peptide, Trebr_0139 Peptide, Slc1a2 Peptide, slc1a2b Peptide
- Background
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SLC1A2 is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EAAT2, GLT-1
Protein Interaction Partner: MYCN,RELA,SLC1A2,JUB,SLC1A2,JUB
Protein Size: 574 - Molecular Weight
- 62 kDa
- Gene ID
- 6506
- NCBI Accession
- NM_004171, NP_004162
- UniProt
- P43004
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