serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2) (N-Term) Peptide
SPTLC2
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all SPTLC2 products
- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SPTLC2 antibody (Catalog #: ARP48652_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
- Synonyms
- HSN1C Peptide, LCB2 Peptide, LCB2A Peptide, NSAN1C Peptide, SPT2 Peptide, hLCB2a Peptide, sptlc2 Peptide, zgc:110661 Peptide, AI173915 Peptide, mKIAA0526 Peptide, Pomt2 Peptide, LCB2a Peptide, SPTLC2 Peptide, serine palmitoyltransferase long chain base subunit 2 Peptide, serine palmitoyltransferase 2 Peptide, serine palmitoyltransferase, long chain base subunit 2 S homeolog Peptide, serine palmitoyltransferase, long chain base subunit 2a Peptide, serine palmitoyltransferase, long chain base subunit 2 Peptide, SPTLC2 Peptide, LOC100446763 Peptide, sptlc2 Peptide, sptlc2.S Peptide, sptlc2a Peptide, Sptlc2 Peptide
- Background
-
SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c
Alias Symbols: KIAA0526, LCB2, SPT2, HSN1C, LCB2A, NSAN1C, hLCB2a
Protein Interaction Partner: SPTLC1
Protein Size: 562 - Molecular Weight
- 63 kDa
- Gene ID
- 9517
- NCBI Accession
- NM_004863, NP_004854
- UniProt
- O15270
-
You are here:
