Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) Peptide
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- Target See all SUMO3 products
- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Sumo1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
- Synonyms
- SMT3A Peptide, SMT3H1 Peptide, SUMO-3 Peptide, Smt3B Peptide, 2810014B19Rik Peptide, AA409334 Peptide, AW121497 Peptide, AW536077 Peptide, D10Ertd345e Peptide, Smt3h1 Peptide, smt3a Peptide, smt3h1 Peptide, fa94a11 Peptide, im:7141764 Peptide, sumo2 Peptide, sumo3 Peptide, sumo3l Peptide, wu:fa94a11 Peptide, wu:fb55d09 Peptide, zgc:65847 Peptide, zgc:85643 Peptide, fc66f10 Peptide, fl11h12 Peptide, wu:fc66f10 Peptide, wu:fl11h12 Peptide, zgc:86902 Peptide, SUMO3 Peptide, ATSUMO3 Peptide, MCO15.12 Peptide, MCO15_12 Peptide, SMALL UBIQUITIN-LIKE MODIFIER 3 Peptide, SUM3 Peptide, SUMO 3 Peptide, small ubiquitin-like modifier 3 Peptide, GMP1 Peptide, PIC1 Peptide, SENTRIN Peptide, SMT3 Peptide, SMT3H3 Peptide, SMTP3 Peptide, SUMO-1 Peptide, Smt3C Peptide, Ubl1 Peptide, small ubiquitin-like modifier 3 Peptide, small ubiquitin-like modifier 3 L homeolog Peptide, small ubiquitin-like modifier 3a Peptide, small ubiquitin-like modifier 3b Peptide, small ubiquitin-related modifier 2 pseudogene Peptide, SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) Peptide, small ubiquitin-like modifier 2 Peptide, small ubiquitin-like modifier 1 Peptide, SUMO3 Peptide, Sumo3 Peptide, sumo3.L Peptide, sumo3a Peptide, sumo3b Peptide, LOC490297 Peptide, sumo3 Peptide, sumo2 Peptide, Sumo1 Peptide
- Background
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Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development.
Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
Protein Interaction Partner: Jun,Junb,Hif1a,Nfkb2,Pou5f1
Protein Size: 101 - Molecular Weight
- 11 kDa
- Gene ID
- 22218
- NCBI Accession
- NM_009460, NP_033486
- UniProt
- P63166
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