Transcriptional Adaptor 3 (TADA3) Peptide
TADA3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TADA3L (TADA3) products
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TADA3L antibody (Catalog #: ARP38786_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))
- Synonyms
- ADA3 Peptide, NGG1 Peptide, STAF54 Peptide, TADA3L Peptide, hADA3 Peptide, Tada3l Peptide, 1110004B19Rik Peptide, AI987856 Peptide, fa03f04 Peptide, tada3 Peptide, wu:fa03f04 Peptide, zgc:63596 Peptide, ada3 Peptide, ada3-A Peptide, ngg1 Peptide, tada3l Peptide, tada3l-a Peptide, ada3-B Peptide, tada3l-B Peptide, transcriptional adaptor 3 Peptide, transcriptional adapter 3 pseudogene Peptide, transcriptional adaptor 3 (NGG1 homolog, yeast)-like Peptide, transcriptional adaptor 3 L homeolog Peptide, transcriptional adaptor 3 S homeolog Peptide, TADA3 Peptide, Tada3 Peptide, LOC732883 Peptide, LOC100061462 Peptide, tada3 Peptide, LOC100619707 Peptide, tada3l Peptide, tada3.L Peptide, tada3.S Peptide
- Background
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Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: ADA3, NGG1, hADA3, TADA3L
Protein Interaction Partner: ADPGK,CCDC101,EIF3J,EP300,FAM107B,HSPA8,ING5,MAGEH1,PIAS4,RARA,RFX1,RXRA,SAP18,TADA2A,TP53,USP5,ZNF7,CCDC101,EIF3J,EP300,ESR1,HSPA8,MYC,RARA,RFX1,RXRA,SAP18,SUPT3H,TADA2A,TAF10,TAF9,TP53,USP22,USP5,ZNF7
Protein Size: 432 - Molecular Weight
- 49 kDa
- Gene ID
- 10474
- NCBI Accession
- NM_006354, NP_006345
- UniProt
- O75528
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