Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) Peptide
TGM2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all Transglutaminase 2 (TGM2) products
- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TGM2 antibody (Catalog #: ARP47471_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2) peptide
TGM2 Reactivity: Human Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
- Synonyms
- G-ALPHA-h Peptide, GNAH Peptide, TG2 Peptide, TGC Peptide, tgm2 Peptide, zgc:101081 Peptide, TgaseII Peptide, TGM2 Peptide, fc12b04 Peptide, wu:fc12b04 Peptide, zgc:136700 Peptide, TGL2 Peptide, G[a]h Peptide, TGase2 Peptide, tTG Peptide, tTGas Peptide, transglutaminase 2 Peptide, transglutaminase 2, C polypeptide A Peptide, transglutaminase 2b Peptide, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) Peptide, transglutaminase 2, C polypeptide Peptide, TGM2 Peptide, tgm2a Peptide, Tgm2 Peptide, tgm2b Peptide
- Background
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Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, TGM2 is the autoantigen implicated in celiac disease.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: TG2, TGC, GNAH, G-ALPHA-h
Protein Interaction Partner: HTT,KPNA4,ACTB,ALDOA,ANXA1,CASP3,EIF5A,FN1,GSTP1,HIST1H2BG,HIST2H2BE,HTT,ITGB1,ITGB3,KPNA3,KPNA4,LTBP1,MAP3K12,PLCD1,PPHLN1,RB1,RHOA,S100A7,SERPINF2,SMAD2,SMAD3,SPARC,TGM2,TMSB4X,TUBB,FN1,GSTP1,KPNA4,PLCD1,RB1,TGM2
Protein Size: 548 - Molecular Weight
- 62 kDa
- Gene ID
- 7052
- NCBI Accession
- NM_198951, NP_945189
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