Transducin-Like Enhancer Protein 2 (TLE2) Peptide
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- Target See all TLE2 products
- TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TLE2 antibody (Catalog #: ARP32347_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TLE2 (Transducin-Like Enhancer Protein 2 (TLE2))
- Synonyms
- TLE2 Peptide, ESG Peptide, ESG2 Peptide, GRG2 Peptide, Grg2 Peptide, mKIAA4188 Peptide, transducin like enhancer of split 2 Peptide, transducin-like enhancer of split 2 Peptide, TLE2 Peptide, Tle2 Peptide
- Background
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TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
Alias Symbols: ESG, ESG2, FLJ41188, GRG2
Protein Interaction Partner: H3F3B,HMGB1,PRDM1,RUNX1,TLE1,UTY,HES1,PRDM1,TLE1,TLE2,UTY
Protein Size: 743 - Molecular Weight
- 80 kDa
- Gene ID
- 7089
- NCBI Accession
- NM_003260, NP_003251
- UniProt
- Q04725
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