Cardiac Troponin T (cTnT) (N-Term) Peptide
cTnT
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Cardiac Troponin T2 (cTnT) products
- Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNNT2 antibody (Catalog #: ARP41717_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
- Synonyms
- CMH2 Peptide, CMPD2 Peptide, LVNC6 Peptide, RCM3 Peptide, TnTC Peptide, cTnT Peptide, Tnt Peptide, CTTG Peptide, Ctt Peptide, RATCTTG Peptide, Tnnt3 Peptide, tnnt2 Peptide, CT3 Peptide, si:ch211-136g2.1 Peptide, troponin T2, cardiac type Peptide, troponin T2, cardiac Peptide, troponin T type 2a (cardiac) Peptide, troponin T2, cardiac type L homeolog Peptide, troponin T2e, cardiac Peptide, TNNT2 Peptide, Tnnt2 Peptide, tnnt2a Peptide, tnnt2.L Peptide, tnnt2e Peptide
- Background
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TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the gene encoding TNNT2 have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Alias Symbols: CMH2, CMPD2, MGC3889, TnTC, cTnT, RCM3, LVNC6
Protein Interaction Partner: MAP3K5,PRKCA,TNNC1,TNNI3,TPM1,TNNI3,TPM1
Protein Size: 295 - Molecular Weight
- 35 kDa
- Gene ID
- 7139
- NCBI Accession
- NM_000364, NP_000355
- UniProt
- A2TDB9
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