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tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (C-Term) Peptide

TSEN2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985658
  • Target See all TSEN2 products
    TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    LRRPLSWKSL AALSRVSVNV SKELMLCYLI KPSTMTDKEM ESPECMKRIK
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TSEN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
    Synonyms
    AU067695 Peptide, RGD1309946 Peptide, PCH2B Peptide, SEN2 Peptide, SEN2L Peptide, tRNA splicing endonuclease subunit 2 Peptide, TSEN2 Peptide, Tsen2 Peptide
    Background
    This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: MGC2776, MGC4440, PCH2B, SEN2, SEN2L

    Protein Interaction Partner: RANBP10,CLP1,TSEN15,TSEN34,TSEN54

    Protein Size: 465
    Molecular Weight
    51 kDa
    Gene ID
    80746
    NCBI Accession
    NM_025265, NP_079541
    UniProt
    Q8NCE0
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