tRNA-splicing Endonuclease Subunit SEN2 (TSEN2) (C-Term) Peptide
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- Target See all TSEN2 products
- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LRRPLSWKSL AALSRVSVNV SKELMLCYLI KPSTMTDKEM ESPECMKRIK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TSEN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))
- Synonyms
- AU067695 Peptide, RGD1309946 Peptide, PCH2B Peptide, SEN2 Peptide, SEN2L Peptide, tRNA splicing endonuclease subunit 2 Peptide, TSEN2 Peptide, Tsen2 Peptide
- Background
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This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC2776, MGC4440, PCH2B, SEN2, SEN2L
Protein Interaction Partner: RANBP10,CLP1,TSEN15,TSEN34,TSEN54
Protein Size: 465 - Molecular Weight
- 51 kDa
- Gene ID
- 80746
- NCBI Accession
- NM_025265, NP_079541
- UniProt
- Q8NCE0
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