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Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term) Peptide

UBA1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985797
  • Target See all UBA1 products
    UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-UBA1 antibody (Catalog #: ARP58687_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
    Synonyms
    A1S9 Peptide, A1S9T Peptide, A1ST Peptide, AMCX1 Peptide, GXP1 Peptide, POC20 Peptide, SMAX2 Peptide, UBA1A Peptide, UBE1 Peptide, UBE1X Peptide, DDBDRAFT_0190927 Peptide, DDBDRAFT_0220497 Peptide, DDB_0190927 Peptide, DDB_0220497 Peptide, Sbx Peptide, Ube-1 Peptide, Ube1x Peptide, a1s9 Peptide, a1s9t Peptide, a1st Peptide, amcx1 Peptide, gxp1 Peptide, poc20 Peptide, smax2 Peptide, uba1a Peptide, ube1 Peptide, ube1x Peptide, uba1 Peptide, uba1b Peptide, ube Peptide, zgc:66143 Peptide, wu:fa01e08 Peptide, wu:fb30f01 Peptide, wu:fi21c11 Peptide, wu:fj14g11 Peptide, ubiquitin like modifier activating enzyme 1 Peptide, ubiquitin activating enzyme E1 Peptide, Ubiquitin-conjugating enzyme E1 Peptide, ubiquitin-like modifier activating enzyme 1 Peptide, ubiquitin-like modifier activating enzyme 1 S homeolog Peptide, ubiquitin-like modifier activating enzyme 1 L homeolog Peptide, UBA1 Peptide, uae1 Peptide, GL50803_4083 Peptide, GL50803_10661 Peptide, Uba1 Peptide, uba1.S Peptide, uba1.L Peptide, uba1 Peptide, ptr3 Peptide
    Background
    UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.

    Alias Symbols: A1S9, A1S9T, A1ST, GXP1, MGC4781, UBA1A, UBE1, UBE1X, AMCX1, POC20, SMAX2

    Protein Interaction Partner: CDK1,GAN,HSPH1,MGMT,SEMA3F,TAF9,TMCC2,TSSC4,BARD1,BRCA1,BTRC,CBL,DZIP3,FANCD2,HGS,HSPH1,NEDD4,NEDD4L,POLR2A,RBCK1,STUB1,UBC

    Protein Size: 1058
    Molecular Weight
    116 kDa
    Gene ID
    7317
    NCBI Accession
    NM_003334, NP_003325
    UniProt
    P22314
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