Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) Peptide
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- Target See all UBE2D3 products
- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBE2D3 antibody (Catalog #: ARP43009_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
- Synonyms
- E2(17)KB3 Peptide, UBC4/5 Peptide, UBCH5C Peptide, eff Peptide, fb36f02 Peptide, wu:fb36f02 Peptide, zgc:56340 Peptide, 1100001F19Rik Peptide, 9430029A22Rik Peptide, AA414951 Peptide, UBE2D3P Peptide, Xubc4 Peptide, e2(17)kb3 Peptide, ubc4/5 Peptide, ubch5c Peptide, ube2d3.1 Peptide, ube2d2 Peptide, xubc4 Peptide, wu:fj13d01 Peptide, zgc:73200 Peptide, ubiquitin conjugating enzyme E2 D3 Peptide, ubiquitin-conjugating enzyme E2D 3 Peptide, ubiquitin conjugating enzyme E2 D3 L homeolog Peptide, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like Peptide, UBE2D3 Peptide, ube2d3 Peptide, Ube2d3 Peptide, LOC100223566 Peptide, ube2d3.L Peptide, ube2d2l Peptide
- Background
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Protein Interaction Partner: BRCA1,DTX3L,IKBKG,MEX3B,NEDD4,NFKB1,NFKBIA,RNF126,RNF5,SAT1,TRIM39,UBE3A,BTRC,DAPK3,DDX58,DTX3L,EPS15,HDAC6,ISG15,MEX3B,NEDD4,POLL,POLM,RBCK1,RNF11,RNF125,RNF126,STAM2,TRIM39,UBASH3B,UBE3A
Protein Size: 147 - Molecular Weight
- 17 kDa
- Gene ID
- 7323
- NCBI Accession
- NM_003340, NP_003331
- UniProt
- P61077
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