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Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3) Peptide

UBE2D3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985813
  • Target See all UBE2D3 products
    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-UBE2D3 antibody (Catalog #: ARP43009_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
    Synonyms
    E2(17)KB3 Peptide, UBC4/5 Peptide, UBCH5C Peptide, eff Peptide, fb36f02 Peptide, wu:fb36f02 Peptide, zgc:56340 Peptide, 1100001F19Rik Peptide, 9430029A22Rik Peptide, AA414951 Peptide, UBE2D3P Peptide, Xubc4 Peptide, e2(17)kb3 Peptide, ubc4/5 Peptide, ubch5c Peptide, ube2d3.1 Peptide, ube2d2 Peptide, xubc4 Peptide, wu:fj13d01 Peptide, zgc:73200 Peptide, ubiquitin conjugating enzyme E2 D3 Peptide, ubiquitin-conjugating enzyme E2D 3 Peptide, ubiquitin conjugating enzyme E2 D3 L homeolog Peptide, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like Peptide, UBE2D3 Peptide, ube2d3 Peptide, Ube2d3 Peptide, LOC100223566 Peptide, ube2d3.L Peptide, ube2d2l Peptide
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

    Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C

    Protein Interaction Partner: BRCA1,DTX3L,IKBKG,MEX3B,NEDD4,NFKB1,NFKBIA,RNF126,RNF5,SAT1,TRIM39,UBE3A,BTRC,DAPK3,DDX58,DTX3L,EPS15,HDAC6,ISG15,MEX3B,NEDD4,POLL,POLM,RBCK1,RNF11,RNF125,RNF126,STAM2,TRIM39,UBASH3B,UBE3A

    Protein Size: 147
    Molecular Weight
    17 kDa
    Gene ID
    7323
    NCBI Accession
    NM_003340, NP_003331
    UniProt
    P61077
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