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anti-Human MTOR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MTOR Antibody (supplied by: Log in to see )

Antigen
Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies
  • 2610315D21Rik
  • AI327068
  • flat
  • FRAP
  • frap1
  • Frap1
  • FRAP1
  • FRAP2
  • RAFT1
  • RAPT1
  • tor
  • wu:fc22h08
Epitope
pSer2448
61
25
25
23
21
20
14
14
14
10
7
6
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
343
163
155
8
2
2
2
1
1
Host
Rabbit
298
44
2
Clonality
Polyclonal
Conjugate
This MTOR antibody is un-conjugated
8
8
7
7
4
4
4
4
4
4
4
4
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
225
115
95
61
54
48
32
20
8
8
3
2
2
2
2
2
1
Supplier
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Catalog No. ABIN498698
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.2089603 ABIN498794 IHC (p) Rabbit pSer2448 Log in to see Polyclonal
0.2089603 ABIN498610 IF IHC (p) WB Rabbit Log in to see Polyclonal
0.2089603 ABIN498885 IHC (p) Rabbit Log in to see Polyclonal
0.2089603 ABIN214561 IF IHC (p) ELISA WB Rabbit AA 2440-2457 Log in to see Polyclonal
0.2089603 ABIN747173 IF (p) IHC (p) Rabbit IgG pSer2481 Log in to see Polyclonal
0.2089603 ABIN213928 ICC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
0.2089603 ABIN447030 ICC IF IHC (p) IHC WB Rabbit Log in to see Polyclonal 1
0.2089603 ABIN214317 IHC (p) ELISA WB Rabbit pSer2448 Log in to see Polyclonal
0.00089375273 ABIN676403 IF (p) IHC (p) Rabbit IgG AA 2436-2492 Log in to see Polyclonal 4
0.00089375273 ABIN117909 EIA IHC (p) WB Rabbit AA 2440-2457, pSer2448 Log in to see Polyclonal 9
0.00089375273 ABIN390217 IF IHC (p) WB Rabbit Ig AA 2459-2488, Ser2481 Log in to see Polyclonal 1
0.00089375273 ABIN747158 IF (p) IHC (p) Rabbit IgG AA 2420-2470, pSer2448 Log in to see Polyclonal 2
0.00089375273 ABIN4620535 EIA IHC (p) WB Rabbit Ig Ser2481 Log in to see Polyclonal 2
0.00089375273 ABIN196962 IF IHC (p) WB Rabbit pSer2448 Log in to see Polyclonal 4
0.00089375273 ABIN272127 IHC (p) WB Rabbit Log in to see Polyclonal 3
0.00089375273 ABIN401642 IHC (p) Rabbit Ser2481 Log in to see Polyclonal 4
0.00089375273 ABIN153493 ELISA EM IHC IHC (p) WB Rabbit IgG pSer2448 Log in to see Polyclonal 4
0.00089375273 ABIN319329 IF IHC (p) WB Rabbit Ser2448 Log in to see Polyclonal 3
0.00089375273 ABIN272040 EIA IHC (p) Rabbit Log in to see Polyclonal
0.00089375273 ABIN303334 EIA IF IHC (p) WB Rabbit AA 2440-2457 Log in to see Polyclonal

Top referenced anti-MTOR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MTOR Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 228 Antibodies 85 Antibodies 80 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies 1 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Immunoprecipitation (IP) 36 Antibodies 13 Antibodies 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 64 Antibodies 30 Antibodies 30 Antibodies
Immunohistochemistry (IHC) 118 Antibodies 48 Antibodies

General

Antigen Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies
Epitope pSer2448
(61), (25), (25), (23), (21), (20), (14), (14), (14), (10), (7), (6), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(343), (163), (155), (8), (2), (2), (2), (1), (1)
Host Rabbit
(298), (44), (2)
Clonality
Polyclonal
Conjugate This MTOR antibody is un-conjugated
(8), (8), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(225), (115), (95), (61), (54), (48), (32), (20), (8), (8), (3), (2), (2), (2), (2), (2), (1)
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Product Details anti-MTOR Antibody

Target Details MTOR Application Details Handling Images
Specificity This antibody detects endogenous levels of mTOR protein when phosphorylated at Ser2448.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details MTOR

Product Details anti-MTOR Antibody Application Details Handling Images back to top
Antigen
Alternative Name mTOR / FRAP1 (FRAP1 Antibody Abstract)
Background MTOR, or FKBP12-rapamycin associated protein (FRAP), is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. In rat, it is a 245- kDa protein (symbolized RAFT1) with significant homology to the Saccharomyces cerevisiae protein TOR1 and has been shown to associate with the immunophilin FKBP12 in a rapamycin-dependent fashion. The FKBP12-rapamycin complex is known to inhibit progression through the G1 cell cycle stage by interfering with mitogenic signaling pathways involved in G1 progression in several cell types, as well as in yeast. The binding of FRAP to FKBP12-rapamycin correlated with the ability of these ligands to inhibit cell cycle progression.Synonyms: FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FRAP, FRAP2, Mammalian target of rapamycin, RAPT1, Rapamycin target protein, Serine/threonine-protein kinase mTOR, TOR
Molecular Weight approx. 289 kDa
Gene ID 2475
NCBI Accession NP_004949
UniProt P42345
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MTOR Antibody Target Details MTOR Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MTOR Antibody Target Details MTOR Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-MTOR Antibody Target Details MTOR Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MTOR antibody (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (pSer2448) (ABIN498698) Immunohistochemistry (IHC) analyzes of mTOR antibody in paraffin-embedded huma...
Western Blotting (WB) image for anti-MTOR antibody (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (pSer2448) (ABIN498698) Western blot (WB) analysis of p-mTOR antibody in extracts from A549 ...