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Browse our Protein Phosphatase 2, Regulatory Subunit B', gamma Proteins (PPP2CA)

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Protein Phosphatase 2, Regulatory Subunit B', gamma Proteins (PPP2CA)
On www.antibodies-online.com are 5 Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) Proteins from 3 different suppliers available. Additionally we are shipping Protein Phosphatase 2, Regulatory Subunit B', gamma Antibodies (63) and many more products for this protein. A total of 71 Protein Phosphatase 2, Regulatory Subunit B', gamma products are currently listed.
Synonyms:
2610043M05Rik, 2700063L20Rik, AI060890, AW545884, B56G, C85228, D12Bwg0916e, mKIAA0044, ppp2r5c, PR61G, si:dkey-241l7.9
list all proteins Gene Name GeneID UniProt
PPP2CA 26931 Q60996
PPP2CA 5527 Q13362
Rat PPP2CA PPP2CA 691318  

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Protein Phosphatase 2, Regulatory Subunit B', gamma Proteins (PPP2CA) by Origin

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More Proteins for Protein Phosphatase 2, Regulatory Subunit B', gamma Interaction Partners

Xenopus laevis Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) interaction partners

  1. Our data also suggest that B56alpha functions pre-midblastula transition , inhibiting Wnt (show WNT2 Proteins) signaling on the ventral side of the embryo, and again during organogenesis, while B56gamma functions primarily post-midblastula transition

Mouse (Murine) Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) interaction partners

  1. The PP2A (show PPP2R2B Proteins) B56gamma regulatory subunit controls PP2A (show PPP2R2B Proteins) substrate specificity in vivo in a manner that cannot be fully compensated for by other B56 subunits.

  2. B56gamma1 suppressed EGF (show EGF Proteins)-induced cell migration on collagen, bound to phosphorylated-ERK (show EPHB2 Proteins), and dephosphorylated ERK (show EPHB2 Proteins).

  3. results suggest that Ppp2r5c expression is regulated by Nrl (show NRL Proteins) during retinogenesis through direct binding to the promoter region of Ppp2r5c

  4. the dynamic nuclear distribution of the B56gamma3 regulatory subunit controls nuclear PP2A (show PPP2R2B Proteins) activity, which regulates cell cycle controllers, such as p27 (show CDKN1B Proteins), to restrain cell cycle progression, and may be responsible for the tumor suppressor function of PP2A (show PPP2R2B Proteins)

  5. A truncated isoform of the protein phosphatase 2A B56gamma regulatory subunit may promote genetic instability and cause tumor progression

  6. Identification of a new B56gamma subunit (B56gamma4) specifically expressed in testis.

  7. PP-2A is less abundant than PP-1 (show PPP1CC Proteins) in the mouse eye and appear to be highly regulated by various regulatory subunits; the genes encoding PP-1alpha/beta, PP-2Aalpha/beta, PP-2A-Aalpha/beta, and PP-2A-B alpha/beta/gamma are all differentially expressed.

Human Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) interaction partners

  1. Mutations in the PP2A (show PPP2R4 Proteins) regulatory subunit B family genes PPP2R5B (show PPP2R5B Proteins), PPP2R5C and PPP2R5D (show PPP2R5D Proteins) cause human overgrowth

  2. our data suggest that hepatic PPP2R5C represents an important factor in the functional wiring of energy metabolism and the maintenance of a metabolically healthy state.

  3. propose that the mechanism for proliferation inhibition and increased apoptosis of K562 cells following PPP2R5C suppression may be related to the alteration of expression profiles of BRAF (show BRAF Proteins), AKT2 (show AKT2 Proteins), AKT3 (show AKT3 Proteins), NFKB2 and STAT3 (show STAT3 Proteins) genes

  4. Differential expression of the transcripts PPP2R5C connects ubiquitin-proteasome system with infection-inflammation in preterm births and preterm premature rupture of membranes.

  5. KIF4A and PP2A (show PPP2R4 Proteins)-B56G and -B56E create a spatially restricted negative feedback loop counteracting Aurora B (show AURKB Proteins) in anaphase.

  6. Data indicate that the regulatory PP2A (show PPP2R4 Proteins) subunit B56gamma mediates suppression of NF-kappaB (show NFKB1 Proteins) resulting in increased NF-kappaB (show NFKB1 Proteins) target gene expression in T cells.

  7. Results show that mutations lost B56gamma tumor-suppressive activity by two distinct mechanisms: one is by disrupting interactions with the PP2A (show PPP2R4 Proteins) AC core and the other with B56gamma-PP2A (show PPP2R4 Proteins) substrates (p53 (show TP53 Proteins) and unknown proteins).

  8. PPP2R5C-siRNA treatment altered gene expression profiles in malignant T cells

  9. structural insight into the PP2A (show PPP2R4 Proteins) holoenzyme assembly and emphasizes the importance of HEAT repeat 1 in B56gamma-PP2A (show PPP2R4 Proteins) tumor-suppressive function

  10. Overexpression of PPP2R5C in T-cell malignancy as well as in myeloid leukemia (show BCL11A Proteins) cells might relate to its proliferation and differentiation.

Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA) Protein Profile

Protein Summary

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with Protein Phosphatase 2, Regulatory Subunit B', gamma (PPP2CA)

  • protein phosphatase 2, regulatory subunit B', gamma (ppp2r5c)
  • protein phosphatase 2, regulatory subunit B', gamma (PPP2R5C)
  • protein phosphatase 2, regulatory subunit B', gamma b (ppp2r5cb)
  • protein phosphatase 2, regulatory subunit B (B56), gamma isoform (Ppp2r5c)
  • protein phosphatase 2, regulatory subunit B', gamma (Ppp2r5c)
  • 2610043M05Rik protein
  • 2700063L20Rik protein
  • AI060890 protein
  • AW545884 protein
  • B56G protein
  • C85228 protein
  • D12Bwg0916e protein
  • mKIAA0044 protein
  • ppp2r5c protein
  • PR61G protein
  • si:dkey-241l7.9 protein

Protein level used designations for PPP2CA

protein phosphatase 2, regulatory subunit B, gamma isoform , protein phosphatase 2, regulatory subunit B (B56), delta isoform , protein phosphatase 2, regulatory subunit B (B56), gamma isoform , protein phosphatase 2, regulatory subunit B', gamma isoform , serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform , protein phosphatase 2, regulatory subunit B', gamma , serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform-like , B56/PP2A gamma , Band 8A , PP2A B subunit isoform B'-alpha-3 , PP2A B subunit isoform B'-gamma , PP2A B subunit isoform B56-gamma , PP2A B subunit isoform PR61-gamma , PP2A B subunit isoform R5-gamma , B' alpha regulatory subunit , renal carcinoma antigen NY-REN-29 , gamma isoform of regulatory subunit B56, protein phosphatase 2A , PP2A B subunit isoform B'-beta , PP2A, B subunit, B' beta isoform , PP2A, B subunit, B' gamma isoform , PP2A, B subunit, B56 gamma isoform , PP2A, B subunit, PR61 gamma isoform , PP2A, B subunit, R5 gamma isoform , protein phosphatase 2A0 B' regulatory subunit beta3 isoform

GENE ID SPECIES
394858 Xenopus (Silurana) tropicalis
423460 Gallus gallus
447462 Xenopus laevis
453170 Pan troglodytes
557208 Danio rerio
100005981 Danio rerio
100017824 Monodelphis domestica
100054977 Equus caballus
100173941 Pongo abelii
100415024 Callithrix jacchus
100466685 Ailuropoda melanoleuca
100600883 Nomascus leucogenys
26931 Mus musculus
5527 Homo sapiens
505757 Bos taurus
691318 Rattus norvegicus
480436 Canis lupus familiaris
100009216 Oryctolagus cuniculus
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