Browse our anti-BOK (BOK) Antibodies

Full name:
anti-BCL2-Related Ovarian Killer Antibodies (BOK)
On www.antibodies-online.com are 65 BCL2-Related Ovarian Killer (BOK) Antibodies from 17 different suppliers available. Additionally we are shipping BOK Proteins (6) and BOK Kits (5) and many more products for this protein. A total of 87 BOK products are currently listed.
Synonyms:
AI847676, AU021146, BCL2L9, bok, Bok-BH3, BOKL, matador, mtd, zgc:64041, zgc:100979

Most Popular Reactivities for anti-BOK (BOK) Antibodies

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anti-Human BOK Antibodies:

anti-Rat (Rattus) BOK Antibodies:

anti-Mouse (Murine) BOK Antibodies:

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Top referenced anti-BOK Antibodies

  1. Human Polyclonal BOK Primary Antibody for EIA, WB - ABIN950672 : Stein, Hua, Lee, Ho, Leow, Toga, Saykin, Shen, Foroud, Pankratz, Huentelman, Craig, Gerber, Allen, Corneveaux, Dechairo, Potkin, Weiner, Thompson,: Voxelwise genome-wide association study (vGWAS). in NeuroImage 2010 (PubMed)
    Show all 5 references for 950672

  2. Human Polyclonal BOK Primary Antibody for IHC (p), WB - ABIN388103 : Hsu, Kaipia, McGee, Lomeli, Hsueh: Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 4 references for 388103

  3. Human Polyclonal BOK Primary Antibody for EIA, IHC (p) - ABIN356820 : Yakovlev, Di Giovanni, Wang, Liu, Stoica, Faden: BOK and NOXA are essential mediators of p53-dependent apoptosis. in The Journal of biological chemistry 2004 (PubMed)

  4. Human Polyclonal BOK Primary Antibody for EIA, IHC (p) - ABIN1450152 : Lockshin, Osborne, Zakeri: Cell death in the third millennium. in Cell death and differentiation 2000 (PubMed)

More Antibodies against BOK Interaction Partners

Human BCL2-Related Ovarian Killer (BOK) interaction partners

  1. Data suggest that endoplasmic reticulum (ER) stress-induced apoptosis in hepatoma cells is regulated by highly labile and ER-associated BCL-2 (show BCL2 Antibodies) family member BOK, which is controlled at level of protein stability by ER-associated degradation components; DNAJB12 (show DNAJB12 Antibodies) is required in hepatoma cells to maintain BOK at low levels and suppress ER stress. (DNAJB12 (show DNAJB12 Antibodies) = DnaJ (Hsp40 (show DNAJB1 Antibodies)) homolog (show DNAJB4 Antibodies), subfamily B (show CYP Antibodies), member 12)

  2. Data suggest that hypoxia-induced expression of BOK in placental cells is regulated via promoter region, hypoxia-response element, and binding of hypoxia-inducible factors (HIF1A (show HIF1A Antibodies), HIF2A/EPAS1 (show EPAS1 Antibodies), HIF1B/ARNT (show ARNT Antibodies)) but is not affected by its antisense transcript.

  3. First evidence for a key role of the BOK-MCL1 (show MCL1 Antibodies) system in regulating autophagy in the human placenta, whereby an adverse environment as seen in preeclampsia tilts the BOK-MCL1 (show MCL1 Antibodies) balance toward the build-up of isoforms that triggers placental autophagy.

  4. Bok may govern IP3R (show ITPR1 Antibodies) cleavage and activity during apoptosis.

  5. The results suggest important roles for Bok and Bcl-X(L (show BCL2L1 Antibodies)) in human ovarian development, follicle maturation and apoptosis.

  6. Data conclude that Mtd (show MT1E Antibodies)-L functions to regulate trophoblast cell proliferation during early placentation and that the elevated levels of Mtd (show MT1E Antibodies) found in PE may contribute to increased trophoblast proliferation.

  7. BOK and NOXA (show PMAIP1 Antibodies) are essential mediators of p53 (show TP53 Antibodies)-dependent apoptosis

  8. A novel Mtd/BOK splice isoform is responsible for trophoblast cell death in pre-eclampsia.

  9. Studies showed that hBok was distributed in both the cytosol and intracellular membranes of healthy cells.

  10. a link between the apoptotic activity and nuclear localization of a pro-apoptotic Bok

Mouse (Murine) BCL2-Related Ovarian Killer (BOK) interaction partners

  1. we show that BOK(C) can permeabilize liposomes, and cooperate with cBID, but its role in directly mediating mitochondrial permeabilization is unclear and may underlie a yet to be determined negative regulation.

  2. Bok controls neuronal Ca(2 (show CA2 Antibodies)+) homeostasis and bioenergetics in seizure-induced neuronal injury.

  3. Study reports that BCL-2 (show BCL2 Antibodies) ovarian killer (BOK) is a bona fide yet unconventional effector of mitochondrial outer membrane permeabilization that can trigger apoptosis in the absence of both BAX (show BAX Antibodies) and BAK (show BAK1 Antibodies).

  4. findings support a selective and distinguishing role for BOK in regulating the apoptotic response to ER stress, revealing--to our knowledge--the first bona fide apoptotic defect linked to Bok deletion

  5. BOK-deficient mice have no readily discernible abnormalities, and its function therefore remains unresolved.

  6. Bok may govern IP3R (show ITPR1 Antibodies) cleavage and activity during apoptosis.

  7. two proapoptotic Bcl-2 family members Bok and Noxa/Pmaip are directly transcriptionally induced by activated MAL and upon activation of the actin-MAL-SRF pathway

  8. Bok protein have a role that largely overlaps with that of other members of the Bcl-2 (show BCL2 Antibodies) family, or may have a function restricted to specific stress stimuli and/or tissues.

  9. Bok represents a cell cycle-regulated pro-apoptotic member of the Bcl-2 (show BCL2 Antibodies) family

BOK Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.

Alternative names and synonyms associated with BOK

  • BCL2-related ovarian killer b (bokb) antibody
  • BCL2-related ovarian killer a (boka) antibody
  • BCL2-related ovarian killer (BOK) antibody
  • BCL2-related ovarian killer (LOC100220512) antibody
  • BCL2-related ovarian killer (Bok) antibody
  • BCL2-related ovarian killer protein (Bok) antibody
  • AI847676 antibody
  • AU021146 antibody
  • BCL2L9 antibody
  • bok antibody
  • Bok-BH3 antibody
  • BOKL antibody
  • matador antibody
  • mtd antibody
  • zgc:64041 antibody
  • zgc:100979 antibody

Protein level used designations for BOK

bcl-2-related ovarian killer protein homolog B , zBok2 , bcl-2-related ovarian killer protein homolog A , zBok1 , BCL2-related ovarian killer , Bcl-2-related ovarian killer , bcl-2-like protein 9 , bcl-2-related ovarian killer protein , bcl2-L-9 , hBOK , apoptosis activator Mtd , protein matador

GENE ID SPECIES
394160 Danio rerio
445218 Danio rerio
701430 Macaca mulatta
768266 Felis catus
100220512 Taeniopygia guttata
666 Homo sapiens
504851 Bos taurus
29884 Rattus norvegicus
395445 Gallus gallus
51800 Mus musculus
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