Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
the human AACS promoter is a PPARgamma (show PPARG ELISA Kits) target gene and this nuclear receptor is recruited to the AACS promoter by direct interaction with Sp1 (show PSG1 ELISA Kits)
Cleavage of AACS by legumain (show LGMN ELISA Kits) is critical for the regulation of enzymatic activity and results in gain-of-function changes.
Knockdown of AACS inhibits differentiation of 3T3-L1 adipocytes and suppresses expression of the adipocyte markers, peroxisome proliferator-activated receptor (show PPARG ELISA Kits) gama and CCAAT/enhancer binding protein alpha (show CEBPA ELISA Kits).
Acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, is controlled by SREBP-2 (show SREBF2 ELISA Kits) and affects serum cholesterol levels.
These results suggest that AACS is regulated by SREBP-2 (show SREBF2 ELISA Kits) and involves in the normal development of neurons.
AACS promoter activity was controlled mainly by C/EBPalpha (show CEBPA ELISA Kits) during adipogenesis.
Activates acetoacetate to acetoacetyl-CoA (By similarity).
, acetoacetyl-CoA synthetase
, acetoacetyl-CoA synthetase-like
, acetoacetyl-coa synthetase
, acetoacetate-CoA ligase
, acyl-CoA synthetase family member 1
, homolog of C. elegans supressor of ras 5 (sur-5)
, protein sur-5 homolog
, AcAc-CoA ligase
, acetoacetyl-CoA ligase