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The study aimed to identify a small set of genetic signatures that may reliably predict the individuals with a high genetic propensity to heroin addiction. A set of 4 genes (JUN (show JUN ELISA Kits), CEBPB (show CEBPB ELISA Kits), PRKCB (show PRKCB ELISA Kits), ENO2 (show ENO2 ELISA Kits), or CEBPG) could predict the diagnosis of heroin addiction with the accuracy rate around 85% in our dataset.
These findings suggest that CEBPG may play an oncogenic role in BCP (show OPN1SW ELISA Kits)-ALL and relies on a mechanism different from CEBPA (show CEBPA ELISA Kits).
HIV-1 Tat (show TAT ELISA Kits)-mediated induction of CCL5 (show CCL5 ELISA Kits) in astrocytes involves NF-kappaB (show NFKB1 ELISA Kits), AP-1 (show FOSB ELISA Kits), C/EBPalpha (show CEBPA ELISA Kits) and C/EBPgamma transcription factors and JAK (show JAK3 ELISA Kits), PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) signaling pathways
High CEBPG expression correlated with poorer clinical prognoses in several human cancers, and C/EBP gam (show CEBPB ELISA Kits)ma depletion decreased proliferation and induced senescence in lung tumor cells.
CEBPG mediates the myeloid differentiation arrest induced by CEBPA (show CEBPA ELISA Kits) deficiency in acute myeloid leukemia (show BCL11A ELISA Kits).
C/EBPgamma positively regulates wound repair both in vitro and in vivo, at least in part, by affecting EGFR (show EGFR ELISA Kits) signaling.
Ig/EBP (C/EBPgamma)is constitutively multiubiquitinated & then degraded by the proteasome. Ubiquitination and degradation are suppressed by forming dimers through the leucine zipper domains.
CEBPG is the transcription factor primarily responsible for regulating transcription of key antioxidant and DNA repair genes in non-bronchogenic carcinoma individuals
CEBPG regulates ERCC5 (show ERCC5 ELISA Kits) expression and this regulation is modified by E2F1 (show E2F1 ELISA Kits)/YY1 (show YY1 ELISA Kits) interactions.
Adult Cebpg-/- mice on a mixed strain background show increased early mortality and altered cancer incidence.
HIV-1 Tat (show TAT ELISA Kits)-mediated induction of CCL5 (show CCL5 ELISA Kits) in astrocytes involves NF-kappaB (show NFKB1 ELISA Kits), AP-1 (show JUN ELISA Kits), C/EBPalpha (show CEBPA ELISA Kits) and C/EBPgamma transcription factors and JAK (show JAK3 ELISA Kits), PI3K/Akt (show AKT1 ELISA Kits) and p38 MAPK (show MAPK14 ELISA Kits) signaling pathways
The senescence-suppressing activity of C/EBPgamma required its ability to heterodimerize with C/EBPbeta (show CEBPB ELISA Kits).
CCAAT/enhancer-binding protein gamma is a critical regulator of IL-1beta (show IL1B ELISA Kits)-induced IL-6 (show IL6 ELISA Kits) production in alveolar epithelial cells.
The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene.
CCAAT/enhancer-binding protein gamma
, CCAAT/enhancer binding protein (C/EBP), gamma
, leucine zipper transcription factor
, c/EBP gamma
, CCAAT/enhancer binding protein gamma
, G-CSF promoter element 1 binding protein
, GPE1-BP (C/EBP gamma)
, GPE1-binding protein
, granulocyte colony-stimulating factor promoter element 1-binding protein
, immunoglobulin enhancer-binding protein 1
, CCAAT/enhancer binding protein ,gamma
, homolog to a human CCAAT/enhancer binding protein - gamma