CCL2 Protein (AA 24-96, partial) (His tag)

Catalog No. ABIN1046668

Product Details

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Protein Type: Recombinant

Protein Characteristics: AA 24-96, partial

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CCL2 protein is labelled with His tag.

Application: SDS-PAGE (SDS), ELISA

Sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMR

Characteristics: Chemotactic factor that attracts monocytes, but not neutrophils.

Purity: 90 %

Application Details

Comment:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 6M guanidine hydrochloride, 20mM Tris

Storage: -20 °C

References

Van Damme, Decock, Bertini, Conings, Lenaerts, Put, Opdenakker, Mantovani: "Production and identification of natural monocyte chemotactic protein from virally infected murine fibroblasts. Relationship with the product of the mouse competence (JE) gene." in: European journal of biochemistry / FEBS, Vol. 199, Issue 1, pp. 223-9, (1991) (PubMed).

Kawahara, Deuel: "Platelet-derived growth factor-inducible gene JE is a member of a family of small inducible genes related to platelet factor 4." in: The Journal of biological chemistry, Vol. 264, Issue 2, pp. 679-82, (1989) (PubMed).

Rollins, Morrison, Stiles: "Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 11, pp. 3738-42, (1988) (PubMed).

Target Details

Target: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Alternative Name: C-C motif chemokine 2 (CCL2 Products)

Synonyms: GDCF-2 Protein, HC11 Protein, HSMCR30 Protein, MCAF Protein, MCP-1 Protein, MCP1 Protein, SCYA2 Protein, SMC-CF Protein, AI323594 Protein, JE Protein, Scya2 Protein, Sigje Protein, MCP-1A Protein, MCP1A Protein, C-C motif chemokine ligand 2 Protein, chemokine (C-C motif) ligand 2 Protein, C-C motif chemokine 2 Protein, CCL2 Protein, Ccl2 Protein, LOC101120093 Protein

Background: Synonyms: Monocyte chemoattractant protein 1,Monocyte chemotactic protein 1,MCP-1,Platelet-derived growth factor-inducible protein JE,Small-inducible cytokine A2

Molecular Weight: 12.6 kD

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection