Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag)

Details for Product No. ABIN1046708, Supplier: Log in to see
Protein Name
  • CXCL10
  • C7
  • IFI10
  • INP10
  • IP-10
  • SCYB10
  • crg-2
  • gIP-10
  • mob-1
  • CRG-2
  • IP10
  • Ifi10
  • Scyb10
  • chemokine (C-X-C motif) ligand 10
  • C-X-C motif chemokine 10
  • CXCL10
  • cxl10
  • Cxcl10
Protein Characteristics
AA 22-98, full length
29
2
1
1
1
1
1
Origin
Human
49
25
8
3
3
1
1
1
Source
Escherichia coli (E. coli)
64
7
2
1
1
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This CXCL10 protein is labelled with His tag.
Application
ELISA
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Sequence VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
Characteristics Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
Purity 90 %
Background Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
Molecular Weight 12.7 kD
UniProt P02778
Comment

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions For Research Use only
Format Lyophilized
Concentration 0.2-2 mg/mL
Buffer Tris-based buffer, 50 % glycerol
Handling Advice Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
Storage -20 °C
Storage Comment Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
Supplier Images
SDS-PAGE (SDS) image for Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag) (ABIN1046708) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag)
Background publications Hensbergen, van der Raaij-Helmer, Dijkman, van der Schors, Werner-Felmayer, Boorsma, Scheper, Willemze, Tensen: "Processing of natural and recombinant CXCR3-targeting chemokines and implications for biological activity." in: European journal of biochemistry / FEBS, Vol. 268, Issue 18, pp. 4992-9, 2001 (PubMed).

Tensen, Flier, Van Der Raaij-Helmer, Sampat-Sardjoepersad, Van Der Schors, Leurs, Scheper, Boorsma, Willemze: "Human IP-9: A keratinocyte-derived high affinity CXC-chemokine ligand for the IP-10/Mig receptor (CXCR3)." in: The Journal of investigative dermatology, Vol. 112, Issue 5, pp. 716-22, 1999 (PubMed).

Proost, De Wolf-Peeters, Conings, Opdenakker, Billiau, Van Damme: "Identification of a novel granulocyte chemotactic protein (GCP-2) from human tumor cells. In vitro and in vivo comparison with natural forms of GRO, IP-10, and IL-8." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 3, pp. 1000-10, 1993 (PubMed).

Luster, Unkeless, Ravetch: "Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins." in: Nature, Vol. 315, Issue 6021, pp. 672-6, 1985 (PubMed).