AG-2 (AA 21-175) protein (His tag)
Origin: Human
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- Target
- AG-2
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-175
- Origin
- Human
- Source
- Human Cells
- Purification tag / Conjugate
- His tag
- Purpose
- Recombinant Human Anterior Gradient Protein 2 Homolog/AG-2/HPC8/AGR2 (C-6His)
- Sequence
- RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTELVDHHH HHH
- Characteristics
- Recombinant Human Anterior Gradient Protein 2 Homolog/AGR2 produced by transfected human cells is a secreted protein with sequence (Arg21-Leu175) of Human AGR2 fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,200 mM NaCl,10 % Glycerol, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- AG-2
- Synonyms
- AG2 Protein, GOB-4 Protein, HAG-2 Protein, PDIA17 Protein, XAG-2 Protein, Agr2h Protein, Gob-4 Protein, mAG-2 Protein, anterior gradient 2, protein disulphide isomerase family member Protein, anterior gradient 2 Protein, AGR2 Protein, Agr2 Protein
- Sub Type
- Fusionprotein
- Target Type
- Viral Protein
- Background
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Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
Alternative Names: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2 - Molecular Weight
- 18.85 kDa
- UniProt
- O95994
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